I want to make science faster.

Our moonshot is really to make virtual cells at ARC and simulate human biology with foundation models.

Why are we so worried about modeling entire bodies over time when we can't do it for an individual cell?

We can figure out how to model the fundamental unit of biology, the cell.

Then from that we should be able to build.

My goal is to really try to figure out ways that we can improve the human experience in our

lifetime.

There are a few things that if we get them right in our lifetime, we'll fundamentally

change the world.

Today we're talking about making science move faster.

My guests are Patrick Shue, co-founder of the Arc Institute,

and A16Z general partner Jorge Condé.

We get into virtual cells and foundation models for biology,

why science gets stuck in incentive knots,

what an alpha fold level movement for cell biology could look like,

and how breakthroughs translate into actual drugs and distance outcomes. Let's get into it. Patrick, welcome to the podcast. Thanks for joining. Thanks for having me on. I've been trying to have you on for years, but finally, I could get your time. Here I am. I'm excited to do it. It's going to be great. For some of the audience who aren't familiar with you and your work at Arc and Beyond, how do you describe what's your moonshot? What is what you're trying

to do? I want to make science faster, right? You know, we can frame this in high-level,

philosophical goals like accelerating scientific progress. Maybe that's not so tangible for people.

I think the most important thing is science happens in the real world. If it's not AI research,

which moves as quickly as you can iterate on GPUs, right? You have to actually move things around.

Atoms, clear liquids from tube to tube to actually make life-changing medicines. And these are things that take place in real time.

You have to actually grow cells, tissues and animals.

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