Episode 142: Long COVID, Intranasal Vaccines, & Booster Dose Timing

Osterholm Update

CIDRAP

Science

4.8 • 2.9K Ratings

🗓️ 19 October 2023

⏱️ 58 minutes

🔗️ Recording | iTunes | RSS

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Summary

In this episode, Dr. Osterholm and Chris Dall discuss the latest national and international COVID trends, an intranasal COVID vaccine candidate, and some recent findings on long COVID. Dr. Osterholm also answers an ID Query about the timing of COVID booster doses and shares two historic public health moments in our new "This Week in Public Health History" segment.

Transcript

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0:00.0	Hello and welcome to the Ostrome Update, a podcast on COVID-19 and other infectious diseases
0:13.5	with Dr. Michael Ostrome. Dr. Ostrome is an internationally recognized medical detective
0:19.1	and director of the Center for Infectious Disease Research and Policy, or SIDRAP, at
0:23.4	the University of Minnesota. In this podcast, Dr. Ostrome draws on nearly 50 years of experience
0:29.0	investigating infectious disease outbreaks to provide straight talk on the latest infectious
0:34.0	disease and public health threats. I'm Chris Dahl, reporter for SIDRAP News, and I'm your
0:39.1	host for these conversations. Welcome back, everyone, to another episode of the Ostrome Update
0:47.4	podcast. As the rollout of the latest COVID-19 booster shots proceeds, researchers with synthetic
0:53.2	biology company Codigenics last week announced promising findings from a phase one trial of its
0:58.4	live attenuated intranasal vaccine candidate, Kovalev. The findings presented at the ID week
1:05.2	meeting in Boston showed that two doses of the intranasal vaccine prompted robust humoral and
1:10.5	cellular immunity in recipients who had not been previously vaccinated against COVID. While it's
1:16.0	still early in the game, the hope is that Kovalev and other intranasal vaccines in development
1:21.6	could provide broader and longer lasting immune responses to the SARS-CoV-2 virus and possibly
1:27.2	reduce transmission. Could these vaccines be the tools that finally put the pandemic in their
1:32.8	rearview mirror? That's one of the topics we're going to discuss on this October 19th episode of
1:37.5	the podcast as we look at the international and national COVID trends. We'll also provide an
1:43.0	update on the variant picture, discuss some new findings on long COVID, talk about the FDA approval
1:48.8	process, answer an ID query on the timing of COVID booster shots, and examine the most recent flu
1:54.8	and respiratory sensational virus data. We'll also bring you the latest installment of this week
2:00.4	in public health history. But before we get started, as always, we'll begin with Dr. Oostrom's
2:06.1	opening comments and dedication. Thanks, Chris. And welcome back to all of you, a part of the podcast
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