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🗓️ 19 December 2024
⏱️ 17 minutes
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0:00.0 | Have you ever wondered if there's a natural way to lower your high blood pressure, |
0:05.1 | guard against Alzheimer's, lose weight, feel better? |
0:07.7 | Well, it turns out there is. |
0:10.7 | Welcome to the Nutrition Facts Podcast. |
0:12.7 | I'm your host, Dr. Michael Greger. |
0:16.6 | You can't buy an epigenetic clock, but you can use one to measure the age of your tissues |
0:21.7 | and cells and to protect health outcomes and life expectancy. |
0:25.6 | In our first story, we look at how epigenetics have surpassed telomere length as the |
0:30.6 | best age predictor. |
0:32.6 | Epigenetics, the differential expression of genes both establishes the character and function |
0:38.7 | of a cell and maintains that identity over time through round after round of cell division. |
0:44.6 | So our heart cell stays a heart cell and divides to make more heart cells instead of |
0:49.0 | skin cells or kidney cells, even though all of our main cells have the same entire complement of DNA to potentially |
0:56.6 | be anything. |
0:58.3 | This is accomplished by methylation chemical markers that silence inappropriate genes |
1:03.3 | in a particular cell. |
1:04.5 | The fidelity of that maintenance of methylation is good, 97 percent to 99.9 percent |
1:10.3 | every division, but not perfect. |
1:12.6 | Over time, those tiny errors may add up and may help explain why the methylation |
1:18.6 | patterns of identical twins drift apart as they age. |
1:22.6 | The epigenetic markers of young identical twins are essentially indistinguishable, but then diverge |
1:28.7 | over time. Identical twins have the same DNA, the same genes, but the difference in gene |
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