Epigenetic Aging and Aging Backwards with Ryan Smith #164
Muscle Intelligence
Ben Pakulski
4.7 • 761 Ratings
🗓️ 8 March 2021
⏱️ 68 minutes
🧾️ Download transcript
Summary
Ryan Smith has previously been a guest on the show to teach us all about peptides. Today he joins me to talk about epigenetic aging, DNA testing, changes in the market and new regulations for peptides, predictions, interventions and individual diagnostics. This is a fascinating conversation for me, as I put my body under a lot of stress during my career and am always interested in longevity and living my best life. I hope you enjoy it as much as I did, and please don't hesitate to contact the team at TruDiagnostic if you have any questions about the fascinating things they are doing.
Ryan Smith graduated with a degree in Biochemistry from the University of Transylvania. In that time, he had multiple research internships, studying large scale protein synthesis and physical chemistry. After graduation, he attended medical school at the University of Kentucky for 2 years. After finishing all the educational curriculum and passing USMLE Step 1 he decided to leave and help open up a pharmacy in the United States that focused on peptide synthesis and formulations for pharmaceutical preparations. Since that time, Tailor Made compounding has become the 4th fastest growing company in healthcare and 21st fastest growing business in the US. Tailor Made Compounding was the first pharmacy to offer an extensive list of peptides in the US and continues research and expansion for the use of these products for the integrative medicine space.
Since then, Ryan has opened many businesses including TruDiagnostic, a company focusing on methylation array based diagnostics for life extension and preventive healthcare.
More about Ryan and TruDiagnostic here: https://trudiagnostic.com/
@ryansmith_PMed
https://www.a4m.com/ryan-smith.html
Previous Episode with Ryan:
Muscle Intelligence #101 A deep-dive on peptides with expert Ryan Smith
Mentioned:
Book: Dr. David Sinclair - Lifespan
Podcast: A New Perspective on Aging: How to Optimize the Quality of your Lifespan with Dr. David Sinclair
Podcast: Optimize Your Life the Philosopher's Way with Brian Johnson
Podcast: Exploring Epigenetics and Optimizing Health in Times of Stress with Dr. Dan Stickler
Sponsor:
BUBS Naturals - you know I love their products just as much as I enjoy working with them - an amazing company, that is always giving back. Check out their Collagen and MCT powder, which goes in my morning coffee every day without fail. Use code MUSCLE at checkout to get 20% off sitewide.
Timestamps:
[0:23] Introduction to guest Ryan Smith
[1:01] Show sponsor BUBS Naturals
[3:12] Changes in the Peptide space in 2020
[6:38] Change in the definition of 'biologics'
[10:25] Quality-variability in compounding pharmacies
[11:54] TruDiagnostic and Ryan's new focus
[12:55] Epigenetics and biological aging
[15:50] What's methylation?
[16:30] Transcribing your DNA
[18:47] Aging (and aging backwards)
[20:00] Testing aging rate
[22:35] Control your epigenetic expression
[24:22] Snapshots of DNA
[25:50] Predictions through epigenetics
[30:25] Interventions and individual diagnostics
[31:15] Show sponsor Optimize.me/muscle code Muscle10
[35:57] Intrinsic vs extrinsic age
[40:05] DHEA
[41:17] Triglycerides and diabetes
[43:20] Applications and predictions
[47:30] Vaccines and genetics
[50:15] Immunsystem support
[52:10] Intervention protocols
[53:50] Vitamin D - liposomal and injections
[56:50] NAD vs NMN
[59:16] Ketone esters
[59:36] Anti-aging peptides
[1:01:05] What your testing kit tells you
[1:03:05] How to find a practitioner
[1:04:10] The benefits of testing
[1:07:20] Disclaimer
Transcript
Click on a timestamp to play from that location
| 0:00.0 | Hey everybody. Welcome back to the muscle intelligence podcast. |
| 0:17.8 | Another amazing episode coming for you today. |
| 0:19.5 | I'm going to shorten up my intro so you can get right to it. There's so much information. Get at your pen and paper because you |
| 0:24.1 | want to take notes on how to live your longest life. We're digging into epigenetics. We're |
| 0:29.3 | digging into peptides and all the best practices you need to be implementing right now to extend |
| 0:34.3 | your life. And whether you're predisposed genetically to obesity or diabetes or heart disease |
| 0:39.4 | or really any of the conventional illnesses, today's guest, Ryan Smith joins me to explain |
| 0:47.2 | it all. |
| 0:47.7 | And he's going to decode it all. |
| 0:48.6 | There's a lot of complex terms. |
| 0:50.3 | You may want to slow down listening speed, listen to it maybe one or two times, and definitely |
| 0:56.0 | take out a pen and paper because there's a lot of action items. |
| 0:58.6 | He hands us to it will apply to our life right now. |
| 1:01.7 | Today's podcast is brought to by Bubbs. |
| 1:04.3 | My favorite, my only MCT powder that goes into my coffee every single day, sometimes goes |
| 1:09.6 | to my pre-workout shake. |
| 1:15.4 | I feel it right away. As soon as I hit that pre-workout, intelligence coffee, which has got my MCT, my lines main from real mushrooms, my alpha-GPC, and my collagen, also from bubs. |
| 1:21.5 | My brain just feels lit. My joints feel amazing. And my body is ready to train and my brain |
| 1:27.0 | is ready to go for the entire day |
| 1:28.6 | because I'm getting that extra brain fuel from the MCT. |
| 1:31.8 | If you guys don't know, MCT is converted in the brain to ketones much faster, immediate energy. |
| 1:37.0 | So it's a very powerful way to start your day or pre-workout. |
... |
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