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TED Talks Daily

Electronic pills that could transform how we treat disease | Khalil Ramadi

TED Talks Daily

TED

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4.111.9K Ratings

🗓️ 25 May 2021

⏱️ 5 minutes

🧾️ Download transcript

Summary

Could a small jolt of electricity to your gut help treat chronic diseases? Medical hacker and TED Fellow Khalil Ramadi is developing a new, noninvasive therapy that could treat diseases like diabetes, obesity, Parkinson's and Alzheimer's with an electronic pill. More targeted than a traditional pill and less invasive than surgery, these micro-devices contain electronics that deliver "bionudges" -- bursts of electrical or chemical stimuli -- to the gut, potentially helping control appetite, aid digestion, regulate hormones -- and even stimulate happiness in the brain.

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Transcript

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0:00.0

Hi, it's Bryce Dallas Howard here, guest hosting today on TED Talks Daily.

0:09.4

Here's a talk from the TED Fellows community, given by medical hacker Khalil Ramadi,

0:14.4

who is inventing the future of medicine with cutting-edge non-invasive technologies for gut and

0:20.2

neuromedicine.

0:21.6

Do you know what a bio-nudge is? You will in five minutes.

0:28.1

For decades, scientists have tried to use brain modulation to treat neurological disorders.

0:35.4

Techniques usually involve sticking wires onto our head and helmets that

0:39.5

immobilized our head and zapping our brain with magnetic or electrical pulses. Given what we now know

0:45.5

about the millions of circuits that our brain has, this was much like trying to fix a pothole by

0:51.0

resurfacing the entire road. Brain modulation can actually come in different forms.

0:56.8

The brain connects with all organs in our bodies through neurons, much like an octopus

1:01.4

as tentacles. This means that diabetes, cancer, autoimmune disorders can all be induced,

1:08.1

affected, and exacerbated by the brain and the nervous system.

1:12.4

This also means that brain modulation can be achieved through different parts of the body

1:16.8

by zapping organs and limbs with electrodes that have usually been implanted with drills and scalples.

1:22.7

Today, however, brain modulation doesn't have to be so invasive.

1:26.6

Some of my colleagues at MIT have discovered that a

1:29.6

potential therapy for Alzheimer's could be watching light of a certain wavelength flash at a

1:35.0

particular frequency. This is an example of something I like to call a bio-nuch. Simple techniques

1:41.3

that target specific circuits in our bodies to achieve a certain outcome,

1:46.1

like using light to slow degeneration in Alzheimer's.

1:49.2

Bionoges don't need to be shocking or jarring.

...

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