4.3 • 1.2K Ratings
🗓️ 14 March 2016
⏱️ 27 minutes
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There is a new genetic technology which promises to revolutionise agriculture and transform our influence over the natural world. Research is well underway to create pigs and chickens immune to pandemic influenza, cereals which make their own fertiliser and mosquitoes engineered to wipe out wild populations of the insects which transmit diseases to humans. These are just three examples of what we could create with CRISPR gene editing.
Should we be worried about this unprecedented power over animals and plants? The potential for good is enormous. The ethical challenges are profound. Professor Matthew Cobb of the University of Manchester explores the brave new world of CRISPR gene editing.
(Photo: Pigs at the Roslin Institute that have been gene-edited with the goal of making them resistant to African Swine Fever virus)
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0:22.0 | There's a new genetic technology that promises to revolutionize agriculture and transform our influence over the natural world. But should we be worried about this unprecedented |
0:25.2 | power over animals and plants? I'm Professor Matthew Cobb of the University of Manchester, |
0:30.9 | and this is Discovery from the BBC World Service. |
0:34.0 | A scientist in the world service. A scientist in London is the joystick |
0:37.0 | a scientist in London is modifying the embryo of a mosquito to see if it's possible to |
0:46.8 | eradicate malaria in parts of sub-Saharan Africa. The same technique is being used to alter the genetic makeup of farm animals. |
0:55.0 | This is the gene editing technology CRISPR. |
0:58.0 | These animals in front of us are involved in a study looking at trying to |
1:05.2 | engineer resilience to a virus called African swine fever virus. |
1:09.2 | CRISPR, CRISPR-CAS 9. It's very quick, it's very reliable, it's very precise. This is an utter revolution. |
1:17.0 | Creating farm animals immune to killer infections might seem like a great idea. But what about using CRISPR to wipe out whole species like disease-carrying |
1:26.3 | insects? |
1:27.3 | I'm alarmed that the debate has jumped way ahead to species elimination when there's so much that needs to be thought about and |
1:35.6 | considered before reaching that point. |
1:37.3 | The gene editing CRISPR into the freshly laid fertilised eggs of the mosquito. |
1:44.0 | Four years ago, |
1:50.0 | researchers from the United States and Europe discovered a remarkable new tool for genetic |
1:55.8 | engineering. It goes under the name of CRISPR. It's quite different from the original technique |
2:01.6 | of genetic modification, which was invented in the 1970s. |
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