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In this powerhouse episode of the Optimal Protein Podcast, Vanessa Spina sits down with legendary muscle metabolism researcher Dr. Arny Ferrando for an in-depth masterclass on essential amino acids, protein timing, aging, anabolic resistance, and how to optimize muscle retention and fat loss—especially during menopause.

Dr. Ferrando shares the latest research from his decades-long career at NASA, the University of Arkansas, and in collaboration with Dr. Robert Wolfe. He breaks down how muscle protein synthesis actually works, what drives anabolic resistance in aging and menopause, and why exercise and essential amino acids must be combined for optimal results. Vanessa and Dr. Ferrando also cover protein myths, high-protein diets, fat loss in older adults, and what new research is revealing about protein needs for women in midlife.

Whether you’re trying to preserve muscle, lose fat, or simply optimize your health, this is a must-listen episode filled with actionable insights and science-backed strategies.

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🔍 What You’ll Learn in This Episode:

• The difference between muscle protein synthesis vs. anabolism

• Why protein turnover is like a dimmer switch—not an on/off switch

• The real role of essential amino acids (EAAs) in muscle building

• Why free-form EAAs outperform BCAAs and even whey for absorption and delivery

• The critical importance of blood flow from exercise in delivering amino acids

• Why peri- and postmenopause triggers anabolic resistance

• How to optimize protein intake during the menopause transition

• Is there a protein limit per meal? Debunking the 30g myth

• Animal vs. plant protein: what the research says about quality and calories

• Is high protein bad for kidneys? Dr. Ferrando debunks the myth

• Why total daily protein matters more than meal timing or distribution

• How to use protein and amino acids during injury, illness, or fat loss

🧠 Key Takeaway:

To build and preserve muscle—especially in midlife and beyond—you need to combine resistance training with high-quality essential amino acid intake. Total daily protein intake is critical, and older adults often need more, not less. Don’t fear high-protein diets—embrace them intelligently to age strong, lean, and healthy.

💡 Mentioned in This Episode:

Free High-Protein Keto Guide

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The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.