Dr. Kyle Gillett: How to Optimize Your Hormones for Health & Vitality

Huberman Lab

Scicomm Media

Science, Health & Fitness, Life Sciences

4.8 • 26.2K Ratings

🗓️ 11 April 2022

⏱️ 179 minutes

🔗️ Recording | iTunes | RSS

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Summary

My guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improve overall health and well-being in both men and women. We discuss how to improve hormones using behavioral, nutritional, and exercise-based tools and safely and rationally approach supplementation and hormone therapies. We discuss testosterone and estrogen and how those hormones relate to fertility, mood, aging, relationships, disease pathologies, thyroid hormone, growth hormone, prolactin, dopamine and peptides that impact physical and mental health and vitality across the lifespan. The episode is rich with scientific mechanisms and tools for people to consider. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Thesis: https://takethesis.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Dr. Kyle Gillett, MD, Hormone Optimization (00:04:10) Sponsors (00:08:24) Preventative Medicine & Hormone Health (00:14:17) The Six Pillars of Hormone Health Optimization (00:17:14) Diet for Hormone Health, Blood Testing (00:20:21) Exercise for Hormone Health (00:21:06) Caloric Restriction, Obesity & Testosterone (00:23:55) Intermittent Fasting, Growth Hormone (GH), IGF-1 (00:29:08) Sleep Quality & Hormones (00:35:03) Testosterone in Women (00:38:55) Dihydrotestosterone (DHT), Hair Loss (00:43:46) DHT in Men and Women, Turmeric/Curcumin, Creatine (00:50:10) 5-Alpha Reductase, Finasteride, Saw Palmetto (00:52:30) Hair loss, DHT, Creatine Monohydrate (00:55:07) Hair Regrowth, Male Pattern Baldness (00:58:12) Polycystic Ovary Syndrome (PCOS), Inositol, DIM (01:04:00) Oral Contraception, Perceived Attractiveness, Fertility (01:10:31) Testosterone & Marijuana or Alcohol (01:14:27) Sleep Supplement Frequency (01:15:34) Testosterone Supplementation & Prostate Cancer (01:20:24) Prostate Health, Dietary Fiber, Saw Palmetto, C-Reactive Protein (01:24:05) Prostate Health & Pelvic Floor, Viagra, Tadalafil (01:30:54) Testosterone Replacement Therapy (TRT) (01:35:17) Estrogen & Aromatase Inhibitors, Calcium D-Glucarate, DIM (01:39:28) Lifestyle Factors to Increase Testosterone/Estrogen Levels, Dietary Fats (01:45:34) Aromatase Supplements: Ecdysterone, Turkesterone (01:47:04) Tongkat Ali (Long Jack), Estrogen/Testosterone levels (01:52:25) Fadogia Agrestis, Luteinizing Hormone (LH), Frequency (01:56:44) Boron, Sex Hormone Binding Globulin (SHBG) (01:58:13) Human Chorionic Gonadotropin (hCG), Fertility (02:04:18) Prolactin & Dopamine, Pituitary Damage (02:08:34) Augmenting Dopamine Levels: Casein, Gluten, Vitamin E, Vitamin B6 (P5P) (02:12:30) L-Carnitine & Fertility, TMAO & Allicin (Garlic) (02:18:19) Blood Test Frequency (02:19:41) Long-Term Relationships & Effects on Hormones (02:25:33) Nesting Instincts: Prolactin, Childbirth & Relationships (02:29:05) Cold & Hot Exposure, Hormones & Fertility (02:32:34) Peptide Hormones: Insulin, Tesamorelin, Ghrelin (02:37:24) Growth Hormone-Releasing Peptides (GHRPs) (02:39:38) BPC-157 & Injury, Dosing Frequency (02:45:23) Uses for Melanotan (02:48:21) Spiritual Health Impact on Mental & Physical Health (02:54:18) Caffeine & Hormones (02:56:19) Neural Network Newsletter, Zero-Cost Support, YouTube Feedback, Spotify Review, Apple Reviews, Sponsors, Supplements, Instagram, Twitter Title Card Photo Credit: Mike Blabac Disclaimer

Transcript

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0:00.0	Welcome to the Huberman Lab podcast where we discuss science and science-based tools for everyday life.
0:09.0	I'm Andrew Huberman and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine.
0:15.0	Today my guest is Dr. Kyle Gillette.
0:17.0	Dr. Gillette is dual board certified in family medicine and obesity medicine and practices out of a clinic in Kansas and via telemedicine.
0:26.0	He provides full spectrum medicine including hormone health, preventive medicine, obstetrics, which is the branch of medicine and surgery concerned with childbirth and the care of women giving birth and pediatrics.
0:38.0	I first learned about Dr. Gillette from a podcast of all things and was immediately struck by the breadth and depth of his knowledge on all things, hormones and hormone optimization.
0:47.0	As you'll see very soon today, Dr. Gillette can teach you how to optimize your hormones using behavioral tools, nutrition, exercise-based tools, supplementation and hormone therapies if those are appropriate for you.
1:00.0	There are many professionals out there including many medical doctors, of course, talking about hormone health.
1:05.0	What really sets Dr. Gillette apart from the pack is his ability to understand how the different factors that I described before, nutrition, supplementation, exercise and hormone therapies,
1:15.0	how those interact with one another and the safest and most rational ways to approach hormone optimization.
1:22.0	During today's episode, you will learn how to optimize your hormones, not just testosterone and estrogen, but also prolact in other hormone pathways that impact your mood, mental health and physical health.
1:33.0	Dr. Gillette is also an avid educator about hormones and other aspects of health.
1:37.0	He does this on zero cost to consumer platforms such as Instagram and other social media on Instagram. He is Kyle Gillette MD.
1:45.0	That's KYLEGILLETT at the end, MD.
1:50.0	So Kyle Gillette MD on Instagram and he is Gillette health on all other platforms including LinkedIn, Twitter, YouTube, TikTok and Facebook.
1:58.0	If you go to his Instagram or his other social media, you will learn a lot about hormone health, about the latest science impacting obesity and metabolic health.
2:07.0	He is a wealth of knowledge and again, he's providing all that information at zero cost to you, the consumer.
2:13.0	What you are soon to hear is a conversation between me and Dr. Gillette about all things hormones and hormone health and hormone optimization.
2:22.0	We dive deep into mechanisms, but we are clear to establish what each word or set of concepts mean.
2:29.0	So if you have no background in biology or even if you do, I'm sure that you'll come away with a wealth of valuable knowledge.
2:35.0	We also talk about specific protocols related again to lifestyle factors, nutrition, supplementation and where appropriate hormone replacement therapy.
2:44.0	I know there's a lot of interest about these topics. Dr. Gillette is very thorough about addressing both male and female issues
	...

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