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Unbiased Science

Don’t You Forget About Me: Unraveling Alzheimer’s Disease

Unbiased Science

@unbiasedscipod

Education, Health & Fitness, Science

4.5622 Ratings

🗓️ 28 August 2024

⏱️ 66 minutes

🧾️ Download transcript

Summary

We are BACK for SEASON FIVE of the pod! In this episode, Dr. Jessica Steier and Dr. Sarah Scheinman discuss Alzheimer's disease and cognitive decline. They cover essential topics including the definition and symptoms of Alzheimer's, the genetic and epigenetic basis of the disease, brain changes associated with Alzheimer's, risk factors such as age, genetics, and lifestyle, modifiable risk factors and prevention strategies, and current treatments and their controversies. The scientists emphasize that maintaining overall health is crucial for brain health. They recommend a combination of lifestyle choices that promote general well-being, which in turn support cognitive health. They explore various treatment options, including cholinesterase inhibitors, NMDA receptor antagonists, and monoclonal antibodies targeting amyloid beta. The conversation highlights the ongoing debates about treatment efficacy and the need for further research. The episode aims to provide valuable insights and alleviate fears surrounding Alzheimer's disease. It concludes with a rapid-fire Q&A segment addressing listeners' questions. All our sources from this episode are available at: https://www.unbiasedscipod.com/episodes/dont-you-forget-about-me-unraveling-alzheimers (00:01) Music and Season Five Welcome (04:30) Introducing Dr. Sarah Scheinman and the Topic of Alzheimer's (07:49) Understanding Alzheimer's Disease and Its Symptoms (10:50) The Genetic and Epigenetic Basis of Alzheimer's (18:23) Risk Factors for Alzheimer's: Age, Genetics, and Lifestyle (26:02) The Role of Amyloid Plaques and Tau Tangles in Alzheimer's (30:37) Promoting Early Diagnosis and Intervention for Alzheimer's (35:21) Breaking Down the Stigma and Building Scientific Literacy (41:51) Treatments for Alzheimer's Disease (46:27) Monoclonal Antibodies and Controversy (53:50) Diagnosing Alzheimer's Disease (55:32) Final Thoughts: Q&A: Common Questions About Alzheimer's Disease Interested in advertising with us? Please reach out to [email protected], with “Unbiased Science” in the subject line. PLEASE NOTE: The discussion and information provided in this podcast are for general educational, scientific, and informational purposes only and are not intended as, and should not be treated as, medical or other professional advice for any particular individual or individuals. Every person and medical issue is different, and diagnosis and treatment requires consideration of specific facts often unique to the individual. As such, the information contained in this podcast should not be used as a substitute for consultation with and/or treatment by a doctor or other medical professional. If you are experiencing any medical issue or have any medical concern, you should consult with a doctor or other medical professional. Further, due to the inherent limitations of a podcast such as this as well as ongoing scientific developments, we do not guarantee the completeness or accuracy of the information or analysis provided in this podcast, although, of course we always endeavor to provide comprehensive information and analysis. In no event may Unbiased Science or any of the participants in this podcast be held liable to the listener or anyone else for any decision allegedly made or action allegedly taken or not taken allegedly in reliance on the discussion or information in this podcast or for any damages allegedly resulting from such reliance. The information provided herein do not represent the views of our employers. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

You're listening to an Airwave Media podcast.

0:06.0

Adobe Express is the quick and easy Create Anything app.

0:10.2

It's a game changer for my business, my go-to for creating content.

0:14.4

From social posts to images, videos, flyers, whatever I need to stand out.

0:20.5

With customizable templates and smart features, it saved me endless hours.

0:25.6

And the best bit, it's free.

0:28.6

Search for Adobe Express to find your host and public health scientists. Welcome to Unbiased Science, where we bring scientific method to the madness.

0:56.1

I'm your host and public health scientist, Dr. Jess Steyer.

1:00.3

And holy moly, we're back for season five of the podcast.

1:04.8

I actually can't really believe that that's a thing.

1:08.8

You know, I joke, but it's so true that I still find it hard to

1:12.2

believe that there are folks who listen to this outside of my mother and her friend group.

1:16.8

So thank you to those who are listening right now. Thank you so much for your ongoing support.

1:22.1

If you're looking at the screen right now, you probably see that there's another human being

1:26.8

on the screen,

1:28.1

Dr. Sarah Scheinman, who I'm going to introduce in just one moment, but I am going to just keep

1:34.3

just awkwardly talking just briefly before we jump into conversation with Sarah. So just a

1:42.6

couple of really quick updates. Summer's been wild on a personal

1:46.8

note, on a professional note. Things have been so busy. It really has not felt like the summer.

1:52.5

It certainly has not been a summer break. That's just not a thing. I'm really excited to share a

1:57.6

little bit more about stuff that I'm doing with my data science consultancy,

2:02.8

really leaning into some of my health policy evaluation expertise. I'm working on some

...

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