Blaze Radio Network.

And now, chewing the fat with Jeff Fisher.

A new study details how the immune and central nervous systems implement sickness behavior.

It makes perfect sense that when we're battling infection, we lose our desire to be around others.

That protects them from getting sick and lets us get much needed rest.

What hasn't been clear is how this behavior change happens.

So in our research published in Cell, scientists at the

Pickauer Institute for Learning and Memory of MIT and Collaborators

used multiple methods to demonstrate casually

that when the immune system cytokine interleukin-1 beta,

you know it as 1 1 l 1b or i l 1b uh researches the reaches the i l 1 receptor

the one i l 1 r1 on nerve neurons in a brain region called the dorsal raf nucleus that activates connections with the intermediate lateral septum to shut down social behavior.

Duh.

According to the studies authors, their findings show that social isolation following immune challenge is self-imposed and driven

by an active neural process rather than a secondary consequence of physiological symptoms of sickness

such as, you know, legathy, legarthlythal, I can't even say the word, such as legurthy and the study co-s senior author, Gloria Choi, associate professor at the Pickauer Institute of MIT's Department of Brain and Cognitive Sciences, along with Jun Howe, Harvard Medical School Associate Professor of Imminology, the paper's co-senior author.

And, of course, the lead author is Lou Yang, a research scientist at Joy's Lab.

So it happens because your body makes it that way.

It's not, you're not sick.

And then you feel like, no, I I, since I'm sick, I probably

shouldn't go out.

Your body is telling you, you're sick, don't go out.

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