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Science Quickly

Do Mitochondria Talk to Each Other? A New Look at the Cell’s Powerhouse

Science Quickly

Scientific American

Science

4.2639 Ratings

🗓️ 21 May 2025

⏱️ 26 minutes

🧾️ Download transcript

Summary

Mitochondria are known as the powerhouse of the cell—but new research suggests they might be far more complex. Columbia University’s Martin Picard joins Scientific American’s Rachel Feltman to explore how these tiny organelles could be communicating and what that might mean for everything from metabolism to mental health. Check out Martin Picard’s full article in the June issue of Scientific American. Tell us what you think! Take our survey for the chance to win some SciAm swag! E-mail us at [email protected] if you have any questions, comments or ideas for stories we should cover! Discover something new everyday: subscribe to Scientific American and sign up for our daily newsletter. Science Quickly is produced by Rachel Feltman, Fonda Mwangi, Kelso Harper, Naeem Amarsy and Jeff DelViscio. This episode was edited by Alex Sugiura, with fact-checking by Shayna Posses and Aaron Shattuck. Our theme music was composed by Dominic Smith. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

Understanding the human body is a team effort. That's where the Yachtel group comes in.

0:05.8

Researchers at Yachtolt have been delving into the secrets of probiotics for 90 years.

0:11.0

Yachtold also partners with nature portfolio to advance gut microbiome science through the global grants for gut health, an investigator-led research program.

0:20.1

To learn more about Yachtolt, visit yawcult.co.

0:22.7

.jp. That's Y-A-K-U-L-T.C-O.JP. When it comes to a guide for your gut, I'm Rachel Felton.

1:00.2

Our guest today is Martin Picard, an associate professor of behavioral medicine at Columbia University.

1:06.6

He's here to tell us all about our mitochondria, what they do for us, and how they can even talk to each other.

1:14.2

If you like to watch your pods instead of just listening, you can check out a video version of my conversation with Martin over on our YouTube page.

1:19.4

Plus, you'll get to see some of the aligning mitochondria we're about to talk about in action.

1:23.8

Martin, would you tell us a little bit about who you are and where you work?

1:29.5

Sure. I work at Columbia University. I'm a professor there, and I lead a team of mitochondrial psychobiologists.

1:34.8

So we try to understand the mind mitochondria connection, how energy and those little living creatures that populate ourselves, how they actually feed our lives and allow us to be and to

1:40.7

think and to feel and to experience life.

1:42.5

Well, before we get into the details, you know, most people know mitochondria is the powerhouse

1:47.8

of the cell, which, fun fact, Scientific American actually coined in the 1950s.

1:52.4

But what are mitochondria to start us off with a really basic question?

1:56.3

Yes, 1957 is the powerhouse of the cell.

1:59.7

There was momentous.

2:00.6

That shaped generations of scientists. And now the powerhouse of the cell. There was momentous. That shaped generations of scientists.

2:03.1

And now the powerhouse analogy is expired.

2:05.9

So it's time for a new perspective.

2:07.6

Really, mitochondria or small living organelles, like little organs of the cell.

...

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