Welcome to episode 539 of the Divine Intervention Podcasts.

In today's podcast I'm going to be addressing a very, very high topic for the USMLE exams.

To be honest with you, this podcast applies to step one step two ck and step three

And in today's podcast I'm gonna be addressing a topic I call 50 high-yield

Quotico steroid factoids to know for the USMLEs.

50 high-yield corticosteroid factories to know for the US-MELES.

So let's jump right into it.

First thing first, we know that the most important corticosteroid is cortisol.

And cortisol is made in the adrenal cortex.

So we know that the adrenal cortex has three layers

the zonal glomerulosa where you make mineral corticoids,

the fascicolata, where you make glucocorticoids like cortisol

and the reticularis where you make sex steroids especially androgens like

D-H-E-A-S. That's factoid number one. Factory number two, if a person has a

state of cortisol excess, what kind of electrode abnormalities would you expect?

Well, one thing people don't realize is that cortisol has some mild mineralocorticoid activity.

So because it has mild mineralocorticoid activity, it can make you lose potassium in your kidneys that can cause hypocellemia.

And it can also make you lose hydrogen ions in your kidneys and that can cause a person to have a metabolic

alkalosis. All right, factory number three. What if they give you a question about a person that has a history

of hashimodos and this person then has hypotension, skin hyperpigmentation

and hyperkilemia. Well, I really hope you're saying, wait, Devine, sounds like this person has

Addisins disease. Remember, another thing for Addison's disease is primary adrenaline sufficiency.

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