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» Divine Intervention Podcasts

DIP Ep 577: USMLE Step 2/3 Rapid Review Series 119

» Divine Intervention Podcasts

Divine-Favour Anene

Medicine, Education, Science & Medicine, Higher Education

4.9929 Ratings

🗓️ 3 March 2025

⏱️ 30 minutes

🧾️ Download transcript

Summary

In this podcast, I continue our rapid review series for the USMLE Step 2CK/3 exams by discussing a host of tricky endocrinology and pharmacology vignettes. HY stuff here for sure. Audio Download

Transcript

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0:00.0

Welcome. My name is Divine. This is episode 577 of the Divine Intervention Podcast. In today's podcast,

0:08.4

we're going to be continuing the rapid review series for the USMaly Step 2, Ski, and Step 3 exams.

0:13.6

This is going to be series 119. Let's begin. So what if they give you a question about a 25-year-old female?

0:21.9

You're told that for the last, you know, three months, you know, she has had a lot of weight gain,

0:29.1

and they describe physical exam findings.

0:31.6

They tell you that her blood pressure is 155 over 95.

0:38.5

And you're told that her current BMI is 32 kilograms per meter squared.

0:44.2

And then you're also told that, you know, she has these appropriate streaks on her lower abdomen.

0:52.1

And then you're asked for the most you know appropriate next and you know

0:56.5

they're giving they give you some labs you notice that a potassium is low you notice that a sodium

1:01.6

is a little bit high or normal and they notice that a bicarb is elevated so what should you be

1:07.1

thinking about here um i would really hope you're saying that divine, this person has a Cushing's syndrome, right?

1:13.9

This person has many of the classic findings.

1:16.2

Like, for example, you notice that this person has, you know, weight gain, right?

1:20.7

Steroids cause a person to gain weight, right?

1:22.8

Really boost your appetite.

1:24.6

If you even think about it, when people have a terminal sickness, many times

1:29.2

they're giving steroids because steroids can improve the appetite. It doesn't improve survival,

1:33.8

but it certainly improves their appetite. And then we see that this person has hypertension

1:38.8

because cortisol has aldosterone-like properties. So if, for example, you take cortisol, cortisol works like aldosterone in a sense.

1:49.0

So it's going to increase sodium and watery absorption in the kidneys.

1:53.2

That can increase a person's blood volume and that can raise your blood pressure.

...

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