Dementia is Diabetes of the Brain: Metabolic Health and Cognitive Decline

High Intensity Health with Mike Mutzel, MS

Mike Mutzel

Fasting, Nutrition, Autophagy, Ketogenic, Keto, Health & Fitness, Ketodiet, Medicine

4.8 • 1.2K Ratings

🗓️ 14 December 2023

⏱️ 15 minutes

🔗️ Recording | iTunes | RSS

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Summary

New research finds dementia is diabetes of the brain, here's the science and ways to optimized brain health and prevent cognitive decline.

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Link to Show Notes: https://bit.ly/3GHKiEp

Studies Mentioned:

Pereira, J. D. et al. Alzheimer’s disease and type 2 diabetes mellitus: A systematic review of proteomic studies. J. Neurochem. 156, 753–776 (2021).

Borovcanin, M. M., Vesic, K., Petrovic, I., Jovanovic, I. P. & Mijailović, N. R. Diabetes mellitus type 2 as an underlying, comorbid or consequent state of mental disorders. World J. Diabetes 14, 481–493 (2023).

Show Notes:

00:00 Alzheimer’s may be a neuro-endocrine disease associated with dysfunctional insulin signaling.

01:30 Long-term alcohol consumption can correlate with early onset dementia.

03:30 Weight gained in your 30s and 40s correlates with a much higher risk of developing Alzheimer’s in your 60s and 70s.

06:05 Type 3 diabetes represents a form of diabetes that selectively involves the brain.

07:30 Pre-diabetes in the elderly is 75%. This predisposes them to cognitive decline.

08:05 Insulin resistance strongly correlates with depression.

08:30 Diabetes predisposes you to cognitive decline.

09:00 Low carb/ketogenic diet significantly improves cognition and quality of life.

11:20 Insulin plays critical roles in the health of your brain.

11:40 Under muscled people over 60 have increased risk for cognitive decline.

12:00 Dementia starts in your 30s.

Transcript

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0:00.0	Memory loss, cognitive decline, and dementia are on the rise.
0:03.4	And today's show, we're going to talk about the metabolic origins honing in on recently published studies
0:07.8	finding the connections between underlying insulin resistance and early onset common of decline in
0:13.7	dementia we know that Alzheimer's disease is the fourth leading cause of
0:17.6	premature mortality in the US and we know that it's the most common form of
0:22.3	dementia now it's been most common form of dementia.
0:23.0	Now it's been known for at least 18 years
0:25.6	that Alzheimer's disease is characterized
0:28.1	by insulin resistance.
0:29.5	And Suzanne de Lamontic coined the term type 3 diabetes.
0:33.2	Her team examined post more brain tissue analysis
0:36.1	of Alzheimer's disease patients,
0:37.7	finding that Alzheimer's disease may be
0:39.8	a neuroendocrine disease associated
0:42.4	with dysfunctional insulin signaling.
0:44.5	Her team coined the term type 3 diabetes
0:47.2	because it harbours elements of both type 1 and type 2 diabetes
0:50.5	since there is both a decrease in a production of insulin and a resistance to
0:54.7	insulin receptors. Now with that in context you would think that long-term care
0:59.2	centers such as adult family homes and memory centers would be feeding patients with dementia or all
1:04.8	summer's disease or even cognitive decline healthy foods.
1:08.1	I have a really good friend who is a health care professional and unfortunately she works almost exclusively with dementia
	...

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