David Sinclair on the Secret to Aging in Reverse | Health Theory

Tom Bilyeu's Impact Theory

Impact Theory

Education, News, News Commentary, Philosophy, Technology, Society & Culture, Business, Self-improvement

4.7 • 5.1K Ratings

🗓️ 19 September 2019

⏱️ 48 minutes

🔗️ Recording | iTunes | RSS

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Summary

Harvard professor David Sinclair believes that not only can we slow aging down, we can actually reverse it. On this episode of Health Theory with Tom Bilyeu, David Sinclair explains the three levels of aging, and what can be done on each level. He describes the lifestyle changes that slow aging down, the drug treatments that begin to stop aging, and experimental new procedures that may actually reverse aging once they are fully developed. This episode is brought to you by: Impact Theory University. Check out Impact Theory University at: http://bit.ly/ImpactTheoryUniversity2 ButcherBox. Use the discount code: "TOM" at butcherbox.com to get 20$ off and FREE BACON PiqueTea. Get up to 17% off their teas + free shipping by going to piquetea.life/impact or check the show notes for my special discount. SHOW NOTES: David explains the information theory of aging [0:59] David explains the difference between genes and the epigenome [2:17] David describes the way that cell stress causes aging [5:20] David explains what proteins are and how they work [6:40] David recommends lifestyle changes to slow down or reverse aging [9:14] David recommends stressing the system by consistent fasting [10:52] David explains why we don’t live as long as whales [15:01] David describes resetting the biological clock [16:16] David explains how to tell when someone is going to die [18:47] David explains why people are taking metformin [20:03] David shares his regimen of exercise and metformin [24:18] David advocates cold exposure [25:28] David explains work he’s done to try to reset the aging clock [29:01] David explains why you don’t want to turn the cellular clock back too far [31:37] David describes the actual process of reversing aging in masses of cells [33:20] David talks about some results with mice that appear to reverse aging [36:40] David shares his father’s story of metformin and NMN use [38:10] David explains the effects of resveratrol [39:07] David describes the kinds of testing he advocates [43:13] David shares the impact he wants to have on the world [45:44] FOLLOW DAVID: WEBSITE: www.lifespanbook.com INSTAGRAM: https://bit.ly/2kPvLjF FACEBOOK: https://bit.ly/2mcAPiq TWITTER: https://bit.ly/2lSh6Vc

Transcript

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0:00.0	When you join Tinder, you might not have been looking for answers, but there were some good
0:05.0	clues, like in the way they smiled with their eyes. Like how they didn't reach free
0:09.6	hand before you'd reach for theirs. And when the time was right, they popped the question,
0:15.1	Will you keep a toothbrush at my place?
0:18.0	From toothbrush proposals to non awkward silences, there's a world of possible connections on Tinder.
0:24.2	Whatever you're looking for, it starts with a swipe, explore the possibilities on Tinder.
0:30.0	Hey everyone, welcome to Health Theory. Today's guest is David Sinclair. He's an acclaimed
0:35.1	Harvard professor who's doing some of the world's most ground-breaking work on human longevity.
0:40.6	He was named by Time Magazine as one of the most influential people on the planet and his new book
0:46.5	Lifespan, the revolutionary science of why we age and why we don't have to, is set to permanently
0:53.2	shift how we think about the inevitability of aging and possibly even death. That is exactly
0:59.0	where I want to start. So this is my favorite topic. I want to live forever. I make no bones about
1:04.2	it. I know that right now though I'm on a collision course with death. So you have a really interesting
1:09.1	theory about what makes us age, if I'm not mistaken, you call the information theory of aging.
1:15.7	So what exactly is the information theory of aging and how do we take advantage of it?
1:20.8	So aging actually has been worked on for about 5,000 years or more. And just in the last 20 years
1:27.1	we've come up with a set of hallmarks of aging. There are about eight of them. And I think many
1:32.4	of your viewers will know that there's teal and mirrored trition in the end. The chromosomes get
1:36.1	shorter. Mydecondria, the power packs, we're running out of energy as we get older. There's a
1:40.2	list along laundry list. And most of the people in my field have said, okay, we've figured out aging.
1:46.1	We've got this list. We put in a nice pie chart and that's it. But what I'm saying is that
1:52.5	why does all that stuff happen? It's not enough just to tick off what happens. You have to understand
	...

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