Clinical Challenges in Surgical Oncology: Intrahepatic Cholangiocarcinoma - Hope in the Face of Nihilism

Behind The Knife: The Surgery Podcast

Science, Health & Fitness, Medicine, Education

4.8 • 1.4K Ratings

🗓️ 23 January 2023

⏱️ 26 minutes

🔗️ Recording | iTunes | RSS

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Summary

Join the Surgical Oncology team from UTSouthwestern and the University of Miami as they tackle a case of intrahepatic cholangiocarcinoma along with the data guiding current treatment paradigms. Listen in as they also review recent clinical trials changing the options available for patients with this dismal biliary tract cancer.

Learning Objectives:
In this episode, we review the workup and diagnostic approach to intrahepatic cholangiocarcinoma with emphasis on the role and benefits of biopsy, lymphadenectomy, operative approach, and the current treatment strategies involving chemotherapy, immunotherapy, and targeted therapies against actionable mutations.

Hosts:
Adam Yopp, MD, FACS (@AdamYopp) is an Associate Professor of Surgery at the UT Southwestern Medical Center and is Chief of the Division of Surgical Oncology. He also serves as Surgical Director of the Liver Tumor Program.

Caitlin Hester, MD (@CaitlinAHester) is a recent graduate of the MD Anderson Complex General Surgical Oncology fellowship and is now a new faculty member in the Division of Surgical Oncology within the Sylvester Cancer Center at the University of Miami where she specializes in surgery for cancers of the liver, pancreas, and other gastrointestinal sites.

Gilbert Murimwa, MD (@GilbertZMurimwa) is a PGY-4 Research Fellow and General Surgery Resident at the UT Southwestern Medical Center. He is studying the pancreatic tumor microenvironment and targeted therapies in the lab of Rolf Brekken within the Hamon Center for Therapeutic Oncology Research.

**Specialty team application link - https://forms.gle/DwrRcMYDaP3a3LaQA Please email [email protected] with any questions.

Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.

If you liked this episode, check out other surgical oncology episodes here: https://behindtheknife.org/podcast-category/surgical-oncology/

Transcript

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0:00.0	In a land not so far far away, the three bears were treating themselves.
0:08.0	Ah, we've put all that Goldilocks business behind us now we've got Skye Protect.
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0:24.0	Live happily ever smarter, with Skye Protect.
0:30.0	Behind the knife, the surgery podcast, relevant and engaging content designed to help you dominate the day.
0:43.0	Are you a passionate surgery educator with something to say, then join behind the knife and let the world hear.
0:58.0	Behind the knife is the number one surgery podcast in the world, with each episode reaching 20,000 listeners.
1:04.0	Our current group of subspecialty teams have created incredibly diverse and engaging content.
1:09.0	But their commitments are nearly finished, and we want to open up the opportunity to all of our listeners.
1:14.0	We're looking for teams of three to four surgeons who will develop one new subspecialty podcast every four months.
1:20.0	To learn more, check out the show notes or contact us at hello at BehindTheNife.org. Applications are due February 13th.
1:27.0	Okay, welcome to BehindTheNife podcast.
1:30.0	Today, we're going to discuss inter-paticlanger carcinoma as usual. I'll introduce my colleagues.
1:37.0	Dr. Caitlin Hester is a assistant professor of surgery and a division of surgical oncology at the University of Miami in the Sylvester Comprehensive Cancer Center.
1:48.0	And Gilbert, Dr. Gilbert, Marimoa is a research resident right now in a PGY3 surgical resident at the University of Texas Southwestern.
1:59.0	I'd like to welcome both of you to the podcast.
2:03.0	So today, we're going to be discussing the workup and interoperative thought process for patients who present with inter-paticlanger carcinoma.
2:12.0	I guess we'll get started right away with you, Gilbert. And how do these patients typically present or commonly present with ICC or inter-paticlanger carcinoma?
2:22.0	Yeah, thanks for the introduction.
2:25.0	So although inter-paticlanger carcinoma is the second most common primary cancer of the liver and it originates in the inter-patic biliary system,
	...

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