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In Our Time: Science

Chromatography

In Our Time: Science

BBC

History

4.51.4K Ratings

🗓️ 4 February 2016

⏱️ 47 minutes

🧾️ Download transcript

Summary

Melvyn Bragg and guests discuss the origins, development and uses of chromatography. In its basic form, it is familiar to generations of schoolchildren who put a spot of ink at the bottom of a strip of paper, dip it in water and then watch the pigments spread upwards, revealing their separate colours. Chemists in the 19th Century started to find new ways to separate mixtures and their work was taken further by Mikhail Tsvet, a Russian-Italian scientist who is often credited with inventing chromatography in 1900. The technique has become so widely used, it is now an integral part of testing the quality of air and water, the levels of drugs in athletes, in forensics and in the preparation of pharmaceuticals. With Andrea Sella Professor of Chemistry at University College London Apryll Stalcup Professor of Chemical Sciences at Dublin City University And Leon Barron Senior Lecturer in Forensic Science at King's College London.

Transcript

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0:00.0

Thank you for downloading this episode of In Our Time, for more details about in our time, and for our terms of use please go to BBC.co.uk.

0:08.0

UK slash Radio 4. I hope you enjoy the program.

0:11.0

Hello, one of the big ideas in chemistry today is chromatography, a way of separating mixed-up

0:17.4

substances to analyze them or extract something useful. In its basic form, it's familiar to generations of school children from when they put a spot of ink at the bottom of a strip of paper,

0:27.0

dip it into water and then watch the pigments spread upwards revealing their separate colours, sometimes if you're lucky, like feathers on a bird of paradise.

0:35.5

With progressive discoveries over 200 years,

0:38.1

some fine tuning and an occasion at a bell prize,

0:41.1

chemists can now sift out the different molecules in just about any substance.

0:45.2

It's a process that has an essential role in many parts of modern life, the cleaning of drinking

0:50.0

water, in forensic science and in medical tests and in making pharmaceuticals.

0:55.8

With me to discuss chromatography are Andrea Sulla, Professor of Chemistry at University College

1:01.1

London, April Stolker, Professor of Chemical Sciences at

1:04.6

Dublin City University and Leon Baron, Senior Lecture in Forensic Science at King's College

1:10.3

London.

1:11.3

Andrea Seller, we've mentioned Paper and Nick, what's going on there and can you, is this, can you give

1:17.0

us that example of chromatography?

1:19.0

Well, this is one of those wonderful little experiments or demonstrations if you will that

1:24.3

everyone should do with their children I mean you know if you've never done this

1:27.2

before then what you really have to do is to get either some kitchen paper or

1:31.2

some blotting paper. I must say that

1:33.2

and just to explain to this is Andrea has decided to turn this studio in a

1:36.9

mini laboratory so he's all over the table which is not very big anyway I'll

...

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