Centrum Multivitamin, Vitamin C, Beta Carotene, Souvenaid, Zinc, or Calcium Supplements for Preventing Alzheimer’s?
NutritionFacts.org Video Podcast
Michael Greger, M.D. FACLM
4.8 • 952 Ratings
🗓️ 8 July 2024
⏱️ 5 minutes
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| 0:00.0 | Alzheimer's patients have significantly lower blood levels of 8 out of 10 antioxidants investigated, |
| 0:12.4 | though of course this could just be a consequence of demented individuals eating diets poor in fruits and vegetables. |
| 0:19.0 | When put to the test, the pre-advised study found no benefit for vitamin E or selenium |
| 0:25.6 | in terms of preventing dementia. |
| 0:27.6 | What about other antioxidants? |
| 0:29.6 | In the Harvard Physicians' Health Study, nearly 6,000 older men were randomized in beta-carotene |
| 0:35.6 | or placebo. |
| 0:38.2 | No difference was found after three years, but after 11 years, those unknowingly taking |
| 0:42.3 | the equivalent of a three-quarter cup of sweet potato worth of beta-carotene a day had slightly |
| 0:47.5 | yet significantly better overall cognitive performance. |
| 0:51.4 | A similar study of older women found no cognitive benefit over a period of nine years. |
| 0:57.1 | Maybe they just didn't wait long enough. Vitamin E and C were also tested. Vitamin E similarly flopped |
| 1:03.8 | throughout, and so did vitamin C up until the last cognitive assessment at around year nine, |
| 1:09.9 | where the vitamin C group appeared |
| 1:11.3 | to pull ahead. However, two trials of a combination of vitamin C, E, and beta-carotene together |
| 1:19.2 | versus placebo, one randomizing 1,500 older patients for seven years, and another truly massive |
| 1:25.8 | one, randomizing more than 20,000 adults for five years, |
| 1:29.5 | both failed to show any cognitive benefit for the antioxidant cocktail. |
| 1:35.3 | What about a multivitamin? |
| 1:37.2 | The physician's health study also tested taking the daily multivitamin, multi-mineral |
| 1:41.2 | supplement Centrum Silver, for 12 years. Compared to those instead |
| 1:45.4 | randomized to placebo, the Centrum Group experienced no cognitive benefit. Suvenate is a nutritional |
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