Cancer Immunology, Immunotherapy, and Exploring the Efficacy of Immune Checkpoint Inhibitors with Dr. Joanne Lysaght
Finding Genius Podcast
Richard Jacobs
4.4 • 1K Ratings
🗓️ 24 August 2021
⏱️ 33 minutes
🧾️ Download transcript
Summary
How can the body be better prepared to fight cancer? By combining immune checkpoint inhibitors with other therapeutic techniques, various beneficial effects can be found.
Listen up to learn:
- Why early cancer cells are more challenging for the body to detect
- What therapies can kill cancer cells with the fewest mutations
- How the mutational burden affects treatment efficacy
Dr. Joanne Lysaght, an Associate Professor, and the Immunotherapy Group Lead at Trinity College, shares her most recent work with cancer immunology and immunotherapy.
Internal factors broadly impact the body's response to tumors determined by where in the body they are and how the tumor micro-environment presents. Therefore, in combination with other regimented treatments, immunotherapies have been found to be especially effective.
Since the tumor microenvironment is critical to treatment, more research is needed to find a broader method. However, with a concentrated effort on new techniques, the percentage of lasting effective treatment will rise as time goes on.
To learn more, vist stjames.ie/cancer/.
Episode also available on Apple Podcasts: apple.co/30PvU9C
Transcript
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| 0:00.0 | Forget frequently as questions. |
| 0:02.0 | Common sense, common knowledge, or Google. |
| 0:05.0 | How about advice from a real genius? |
| 0:07.0 | 95% of people in any profession are good enough to be qualified in license. |
| 0:11.0 | 5%? |
| 0:12.0 | Go above and beyond. |
| 0:13.0 | They become very good at what they do. |
| 0:15.0 | But only 0.1% are real geniuses. |
| 0:18.0 | Richard Jacobs has made his life's mission to find them for you. |
| 0:22.0 | He hunts down and interviews geniuses in every field. |
| 0:25.0 | Sleep science, cancer, stem cells, ketogenic diets, and more. |
| 0:29.0 | Come the geniuses. |
| 0:30.0 | This is the Finding Genius Podcast. |
| 0:33.0 | The Richard Jacobs. |
| 0:38.0 | Before we begin, a note from our sponsor. |
| 0:40.0 | I'm Richard Jacobs, executive director of the Nonprofit Finding Genius Foundation, and host of the Finding Genius Podcast. |
| 0:46.0 | In late 2016, I was re-rended at 65 miles an hour by a truck on the highway, which sent me off-road into a ditch. |
| 0:54.0 | The impact of the collision gave me a concussion and other injuries. |
| 0:58.0 | At the hospital, a CT scan showed that I had thyroid nodules, which turned out to be cancer. |
| 1:03.0 | It was then when I had a biopsy my neck that I realized, even if I was a million there, I wouldn't want a second or a third biopsy due to the pain and the invasiveness of it. |
| 1:12.0 | And appointments at that time for thyroid experts were three to six months out. |
| 1:16.0 | And I was worried about dying now, even if that was irrational. |
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