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The Constant: A History of Getting Things Wrong

By Heart, Part 1

The Constant: A History of Getting Things Wrong

Mark Chrisler

Science, Natural Sciences, Design, Arts, History

4.7851 Ratings

🗓️ 29 July 2025

⏱️ 50 minutes

🧾️ Download transcript

Summary

Here's one to remember. Send me your best "I bet you didn't know that" story in an audio file to ⁠⁠⁠⁠[email protected]⁠⁠⁠⁠Check out: ⁠⁠⁠⁠indeed.com/theconstant⁠⁠⁠⁠ now to start hiringVisit our ⁠⁠⁠⁠Patreon here⁠⁠⁠⁠. You too can get ad-free, early episodes, starting now!⁠⁠⁠⁠​​⁠⁠⁠⁠ ⁠⁠⁠⁠ BUY OUR MERCH, YOU FILTHY ANIMALS!⁠⁠⁠⁠​The Constant is part of the ⁠⁠⁠⁠Airwave Media⁠⁠⁠⁠ podcast network.​​ ​​ ​Interested in advertising on The Constant? Email ⁠⁠⁠⁠[email protected]⁠⁠⁠⁠ to get on board! Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

Click on a timestamp to play from that location

0:00.0

You're listening to an Airwave Media podcast.

0:04.6

I've ruled out uni because I want to live at home.

0:07.0

I've ruled out uni because I want to earn money.

0:10.3

I've ruled out uni because of my grades.

0:14.7

Study with the Open University and there's no need to rule out anything.

0:18.6

With our respected degrees, you can learn from home and work alongside

0:21.6

study. We're open to all. Plus, you'll have the support of expert tutors. So rethink your

0:28.2

future with the degree you didn't think was possible. The Open University. The future is open.

0:34.5

We've grown up surrounded by beauty ideals that promised confidence but often delivered

0:39.3

shame. In a special episode of a millennial mind, I sat down with Nicola Adams to explore how

0:45.0

appearance-based compliments and body talk shape our self-worth without us realizing it. In partnership

0:51.0

with the Dove Self-esteem Project, we unpack the tools to change the conversation

0:55.2

for ourselves and for future generations. Listen now and download the free body confidence journal

1:01.1

at Dove.com forward slash Y2K.

1:05.4

Charles Epstein was a geneticist back when most people didn't know what a geneticist was.

1:13.5

In the 1950s, before Epstein, another geneticist, Jerome Lejeurene, had been researching the cause

1:20.1

of Down syndrome. He knew it had to be something that affected individuals at the very earliest

1:25.0

stages of development, because he could see telltale signs of

1:28.6

the syndrome in patient's fingerprints. Fingerprints form extremely early in embryonic development,

1:36.7

and once they're set, they don't change. So, Down syndrome, Lejean thought, had to be genetic. But in the

1:43.5

1950s, it was hard to get more specific than that.

1:47.0

Genetics was a novel field, and little was known about how it worked.

...

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