Brigitte Macron, wife of French President Emmanuel Macron, has accused ten people of posting malicious comments about her, claiming she was a born a man, something Macron says is completely untrue. Her case is in court in France today and, if found guilty, the eight men and two women standing trial could face up to two years in prison. Sophie Pedder, Paris Bureau Chief at The Economist and Sarah Ditum, columnist at The Times, explain the significance of the trial.

A study in Sweden has found that some adults who have had a diagnosis of autism or ADHD as children would like to be considered for a de-diagnosis due to stigma and sometimes restrictions associated with the condition. Nuala McGovern talks to Dame Uta Frith, Emeritus Professor of Cognitive Development at University College London, and psychologist Sebastian Lundström, from the University of Gothenberg, who is one of the study’s researchers.

What if all your dreams come true and you still find yourself a bit grumpy? That’s the brilliantly blunt question at the heart of Laura Smyth's stand-up tour, Born Aggy. Laura’s journey into comedy wasn’t exactly textbook. She left behind a career in teaching, was diagnosed with Stage 3 breast cancer that same year and - just two weeks after finishing treatment - was on stage in Live at the Apollo. She joins Nuala in the studio.

The safety of some manicures has been called into question after the EU banned the use of TPO, a key ingredient in many gel polishes, due to fertility risks in animal trials. Melissa Wright tells us about producing her own line of gel nail products that don't contain TPOs and Dr Naila Dinani, Consultant Dermatologist at the Royal United Hospital in Bath, explains the risks.

Presenter: Nuala McGovern Producer: Simon Richardson