The content of this podcast is provided for general informational purposes only

and is not intended as, nor should it be considered a substitute for professional medical advice.

Sweaty and pissed. Sweaty and pissed. Manopause makes me sweaty and pissed.

Hello, sweaty and pissed listeners. This is Karen Nicholl, family nurse practitioner in for

sweaty and pissed. Manopause and more. I have some great listener questions to share today

and hopefully I will provide some useful answers. You know, this show is always evolving and our

podcast name is evolving also. We will be known as itchy and bitchy. And I suspect that for those

who are listening to this podcast, you will get that. And now on to our listener questions.

Penny asks, is it possible for a low dose of estradiol 0.5 milligrams to cause sore breasts?

I have had a total hysterectomy and current mammogram that was fine. But I have breast

soreness off and on. Penny is also wondering if this is something that happens to others.

And Penny, I'm sure it does and that's why I think answering your question so that the other

listeners can hear it would be very helpful. So yes, when you're taking estrogen, especially

estradiol, which is one of our three forms of estrogen in our body, we have estradiol,

estradiol and estrone. And estradiol is our most stimulatory form of estrogen. So it can

and will stimulate breast tissue. So sometimes when the estradiol levels are too high,

they will cause that elevation will cause breast tenderness. So sometimes that happens because we're

just not clearing and tabolizing estrogen appropriately. So one thing that can really help if

you're remaining on estradiol tabs is to add diendol methalel dim, for short, D-I-M, D-S-N-Dog,

M is a Mary, 100 milligrams twice a day. If you ever have breast tenderness, it will help clear

some extra estrogen from your body, resolve the breast tenderness. And once the breast tenderness

is resolved, you can stop the supplement. I do have some patients who take it all the time,

...