Bloodwork of Centenarians VS Non-Centenarians Revealed: 3 Blood Tests to Focus On

High Intensity Health with Mike Mutzel, MS

Mike Mutzel

Fasting, Nutrition, Autophagy, Ketogenic, Keto, Health & Fitness, Ketodiet, Medicine

4.8 • 1.2K Ratings

🗓️ 7 October 2023

⏱️ 18 minutes

🔗️ Recording | iTunes | RSS

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Summary

A fascinating new study finds common biomarkers predict the odds of living to 100 years of age.

This 35-year study in 44,000 adults found high-cholesterol and low blood glucose were linked with higher odds of reaching 100 years of age.

Here’s a breakdown of these interesting findings: https://bit.ly/3LI6PnM

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Show Notes:

03:00 2.7% of participants reached their 100th birthday.

03:30 Non-centenarians had double or triple the rates of common conditions.

04:00 Cardiovascular disease decreases your health span and life span.

05:30 Higher total cholesterol is associated with becoming a centenarian.

07:30 Centenarians had lower levels of blood glucose.

08:20 GGT liver enzyme test reflects the turnover of glutathione and oxidative stress.

10:40 Uric acid is an indirect marker of inflammation, and is low in centenarians.

12:00 Cholesterol may be protective.

15:45 Higher levels of total cholesterol and iron, and lower levels of glucose, creatinine, uric acid, AST, GGT, and ALP, total iron binding capacity and LDH were associated with a greater likelihood of becoming a centenarian.

17:30 Improve GGT levels by improving glutathione health and avoiding drinking alcohol.

18:30 Minimize intrahepatic fat with fasting, exercise, and low carb nutrition.

24:45 ApoB to A1 ratio gives insight into lipoprotein health.

27:50 A short term cold can raise iron levels.

Transcript

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0:00.0	With so much talk about blue zones and longevity as of late, I wanted to share with you a
0:03.6	recently published study that found that common lab tests, like total cholesterol, glucose,
0:07.8	ureac acid, and others, are strongly linked with the odds of reaching 100 years of age.
0:13.4	We are talking about a study titled Blood Biomarker Profiles and Exceptional Longevity.
0:18.0	Comparison of Centenarians and Non-Sentenarians in a 35-year follow-up study of the Amoris
0:23.5	cohort. The Amoris acronym stands for the April-Liper protein mortality risk cohort.
0:28.8	This cohort has been tracked for over 35 years in Sweden.
0:32.3	There was over 44,000 subjects in this particular cohort.
0:36.2	Their blood tests were tracked between the years 65 of age up to their 100th birthday.
0:41.6	It's sad to mention that only about 1.2% of these study subjects, about 1200 subjects,
0:48.3	out of 44,000 subjects reached their 100th birthday in this particular study.
0:54.3	And we're going to hone in on common biomarkers that were strongly associated with the increased
0:59.6	odds of reaching 100 years of age, focusing on things like total cholesterol,
1:04.4	serum glucose, ureac acid, liver function tests honing specifically on GDT.
1:09.9	There's three of these ALT, AST, and GDT. We're going to focus on GDT.
1:13.4	You will learn why in just a moment. But this is a really important study, I think, because
1:17.6	I recommend you get your lab's tested at least once a year or every 18 months,
1:21.6	and you can start to look at trends. Now, the study doesn't fully elucidate the interpretations
1:27.6	in the direction of causality. But suffice it to say in my sort of takeaway from this study is,
1:33.0	if we can keep our biomarkers in line with what is associated with an increase
1:37.6	odds of reaching 100 years of age, at the bare minimum, we will reduce the odds of getting
1:42.1	a different disease like myocardial infarction, having a heart attack, having peripheral
	...

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