Biological Youthfulness Reprogrammed: Is It Possible?

Finding Genius Podcast

Richard Jacobs

Health, Extracellularvesicles, Crisprcas9, 3dbioprinting, Medicine, Cancer, Health & Fitness, Biotech, Bioscience, Microbiome, Ketogenicdiets

4.4 • 1K Ratings

🗓️ 4 May 2021

⏱️ 27 minutes

🔗️ Recording | iTunes | RSS

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Summary

Can the aging process actually be reversed or prevented? The answer to this age-old question is explored in today’s show.

Tune in to learn:

What changes about the way DNA is read as we get older, and how this could hold the key to reversing cellular aging
What differs between old and young tissues, and why they heal differently
Whether it’s the loss of stem cells or the loss of function of stem cells that might explain the aging process

New research on the biological basis of tissue rejuvenation potential suggests that developing therapeutics for the restoration of old and damaged tissues is possible.

With the use of machine learning, hundreds of thousands of small molecules are being screened for activities which promote rejuvenation and youthfulness in cells and tissues. Once identified, those small molecules are converted into pill form and given to mice that are aging rapidly, or that are likely to develop an age-related disease.

Researchers then look at whether these drugs really do create the desired effect: the delay, reversal, or prevention of tissue aging and disease.

Press play for an in-depth discussion of all this and more.

Episode also available on Apple Podcasts: apple.co/30PvU9C

Transcript

Click on a timestamp to play from that location

0:00.0	Forget frequently asked questions, common sense, common knowledge or Google, how about advice from a real genius?
0:07.0	95% of people in any profession are good enough to be qualified in license, 5%
0:12.0	They become very good at what they do, but only 0.1%
0:17.0	A real genius, Richard Jacobs has made it his life's mission to find them for you.
0:22.0	He hunts down and interviews geniuses in every field, sleep science, cancer, stem cells, ketogenic diets and more.
0:29.0	Here come the geniuses, this is the Finding Genius Podcast, the Richard Jacobs.
0:36.0	Quick note before we begin, the Finding Genius Foundation, as part of the Finding Genius Podcast, has recently completed a book about understanding viruses.
0:46.0	So the creation of this book was to interview 100 virologists, ask them a lot of deep difficult questions, take the most difficult questions, and then re-interview the top 25 or so,
0:57.0	and ask them the hardest questions I could think of.
1:00.0	And we compile that all into a book, so you'll see question and 4 or 5 experts answers.
1:05.0	Question, 4 or 5 experts answers. There's about 30 questions in the book. I think it's a great read for the layperson and for the researcher.
1:12.0	Talks about a lot of speculation in the world of viruses, such as, are they alive or not, and why is it important?
1:18.0	Why do viruses go latent or hidden or uneffective or sit in a person or an animal or another creature for weeks, months, years, and then suddenly become virulent and affect that person?
1:29.0	So there's a lot of really provocative questions in the book. It's now on Amazon, so if you go to Amazon and type in Finding Genius, you'll see the book on viruses. It's also on Kindle.
1:38.0	The audible version is in production and should be ready in approximately a month, but if you want to go and order it now, you can do so again by going to Amazon or Kindle or go to FindingGeniusFoundation.org and go to publications.
1:51.0	There's an opportunity as well to get the transcripts of all the interviews and to hear the original interviews themselves.
1:57.0	If we could put them all together, the book would be about a thousand pages, but we condense them down to make it juicy and concise and tight and very interesting.
2:05.0	So I hope you'll check out the book. We're now working on one about cancer, but this is going to be our goal is three times a year to come out with these masterclass books that I think will inspire new scientific research and I hope you'll check it out. Thank you.
2:17.0	Hello, this is Richard Jacobs with the FindingGenius podcast, part of the FindingGenius Foundation. We're going to talk about potentially reversing aging and treating disease. So thanks for coming.
2:28.0	My pleasure. Yeah, tell me a bit about your research.
2:31.0	Those listening, we've been interested in the biology of aging for a long time and really the question of why we age and how we age and most relatively, is there anything we can do about it?
2:43.0	So we've studied aging in the sense of how tissues repair themselves well when we're young and less well when we're old.
	...

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