4.4 • 859 Ratings
🗓️ 24 October 2025
⏱️ 16 minutes
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Advice on how to get good sleep is everywhere, with the market for sleep aids worth more than US$100 billion annually. However, scientists warn that online hacks and pricey tools aren’t always effective, and suggest that lessons learnt about the workings of a network of biological clocks found in the human body could ultimately lead to improved sleep.
This is an audio version of our Feature: How to get the best night’s sleep: what the science says
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| 0:00.0 | This is an audio long read from nature. In this episode, How to Get the Best Night's Sleep, |
| 0:09.5 | what the science says, written by Lynn Peoples and read by me, Benjamin Thompson. |
| 0:16.5 | From TikTok videos touting mouth tape and weighted blankets to magazines ranking insomnia curbing |
| 0:23.5 | pillows, sleep advice is everywhere. And it's no wonder, people all over the world complain |
| 0:31.0 | of insomnia and not getting enough sleep, driving a market for sleep aids worth more than |
| 0:36.3 | 100 billion US dollars annually. |
| 0:39.8 | But scientists warn that online hacks and pricey tools aren't always effective. |
| 0:46.0 | And failed attempts to remedy the situation could have negative effects, says Andrew Mackhill, |
| 0:52.1 | a circadian scientist at Oregon Health and Science University in Portland. |
| 0:57.6 | It could discourage people from finding help and things could get worse, he says. |
| 1:03.8 | Instead, researchers point to the lessons coming from circadian science, which, over the past |
| 1:10.1 | five decades has exposed a network of biological clocks |
| 1:14.4 | throughout the body. This timekeeping machinery ensures that physiological systems are primed to do |
| 1:22.0 | the right things at the right times, such as defend against pathogens, digest food and sleep. But circadian clocks |
| 1:31.5 | don't cycle precisely on their own. To stay in sync and function optimally, they need regular |
| 1:38.4 | calibration from sunlight, daily routines and other cues. Modern life doesn't often cooperate. People spend much of |
| 1:48.1 | their time indoors. They eat late into the night. They shift sleep schedules between workdays |
| 1:53.8 | and weekends, effectively jet lagging themselves. The toll is steep. In the short term, circadian disruption and insufficient sleep can reduce cognition, |
| 2:05.7 | mood and reaction time. In the long term, they can increase risks of infections, diabetes, |
| 2:12.2 | depression, dementia, cancer, heart disease and premature death. |
| 2:23.8 | For better sleep and overall health, Mackhill and other scientists emphasize three basics. |
| 2:30.3 | Contrasting light and dark, consolidating meal times and keeping sleep times consistent. |
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