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Nature Podcast

Audio long read: How to get the best night’s sleep — what the science says

Nature Podcast

[email protected]

Science, News, Technology

4.4859 Ratings

🗓️ 24 October 2025

⏱️ 16 minutes

🧾️ Download transcript

Summary

Advice on how to get good sleep is everywhere, with the market for sleep aids worth more than US$100 billion annually. However, scientists warn that online hacks and pricey tools aren’t always effective, and suggest that lessons learnt about the workings of a network of biological clocks found in the human body could ultimately lead to improved sleep.


This is an audio version of our Feature: How to get the best night’s sleep: what the science says


Hosted on Acast. See acast.com/privacy for more information.

Transcript

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0:00.0

This is an audio long read from nature. In this episode, How to Get the Best Night's Sleep,

0:09.5

what the science says, written by Lynn Peoples and read by me, Benjamin Thompson.

0:16.5

From TikTok videos touting mouth tape and weighted blankets to magazines ranking insomnia curbing

0:23.5

pillows, sleep advice is everywhere. And it's no wonder, people all over the world complain

0:31.0

of insomnia and not getting enough sleep, driving a market for sleep aids worth more than

0:36.3

100 billion US dollars annually.

0:39.8

But scientists warn that online hacks and pricey tools aren't always effective.

0:46.0

And failed attempts to remedy the situation could have negative effects, says Andrew Mackhill,

0:52.1

a circadian scientist at Oregon Health and Science University in Portland.

0:57.6

It could discourage people from finding help and things could get worse, he says.

1:03.8

Instead, researchers point to the lessons coming from circadian science, which, over the past

1:10.1

five decades has exposed a network of biological clocks

1:14.4

throughout the body. This timekeeping machinery ensures that physiological systems are primed to do

1:22.0

the right things at the right times, such as defend against pathogens, digest food and sleep. But circadian clocks

1:31.5

don't cycle precisely on their own. To stay in sync and function optimally, they need regular

1:38.4

calibration from sunlight, daily routines and other cues. Modern life doesn't often cooperate. People spend much of

1:48.1

their time indoors. They eat late into the night. They shift sleep schedules between workdays

1:53.8

and weekends, effectively jet lagging themselves. The toll is steep. In the short term, circadian disruption and insufficient sleep can reduce cognition,

2:05.7

mood and reaction time. In the long term, they can increase risks of infections, diabetes,

2:12.2

depression, dementia, cancer, heart disease and premature death.

2:23.8

For better sleep and overall health, Mackhill and other scientists emphasize three basics.

2:30.3

Contrasting light and dark, consolidating meal times and keeping sleep times consistent.

...

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