ANGEL: Threshold VC’s Emily Melton on market distortion, healthcare investing & culture | E1693
This Week in Startups
Jason Calacanis
4.2 • 1.4K Ratings
🗓️ 8 March 2023
⏱️ 58 minutes
🧾️ Download transcript
Summary
Emily Melton joins Molly to discuss her early days in venture and what she learned while working at DFJ (1:30). Then, they talk about the barriers that healthcare imposes on entrepreneurship (17:22), building a diverse culture within venture capital (29:53), market distortions, and how to optimize for a down market (38:42).
(0:00) Molly kicks off the show
(1:30) Getting started in Venture Capital
(8:12) LinkedIn Jobs - Go to https://linkedIn.com/angel and post your first job for free
(9:38) Learnings from working at DFJ
(17:22) Healthcare being a barrier to entrepreneurship
(20:11) Prenuvo - Get $300 off at http://prenuvo.com/twist
(21:41) Threshold Ventures’ fund mechanics
(26:15) Investing in Tia: Healthcare solutions for woman
(29:53) Building culture
(37:45) Pilot - Get 20% off the first 6 months at https://pilot.com/twist
(38:42) Optimizing for a down market
(52:13) What’s next?
FOLLOW Emily: https://twitter.com/emelton
FOLLOW Jason: https://linktr.ee/calacanis
FOLLOW Molly: https://twitter.com/mollywood
Transcript
Click on a timestamp to play from that location
| 0:00.0 | Hey, everybody. Welcome to Wednesday and the Angel series. We have another incredible three-cycle |
| 0:05.2 | investor with us today. This series is incredible. Emily Melton is the co-founder and managing |
| 0:11.3 | partner at threshold BC. And she's just awesome. We're going to talk about healthcare and how |
| 0:18.5 | mad it makes us and all the ways that we want to fix it. Company culture, how she invested in Redfin. |
| 0:24.2 | That's actually how we know each other. How focus is super important as an investor and an |
| 0:29.9 | investing thesis. And then some of the distortions that we've seen over multiple cycles that were |
| 0:35.8 | the same. Others that were a little bit new, for example, founders getting that opportunity to sell |
| 0:40.5 | secondaries during this latest level and maybe making so much money that they don't want to run |
| 0:45.7 | their startup anymore. We cover a lot of ground here. The series is amazing. This interview is |
| 0:49.7 | amazing. You're going to love it. Stick with us. This week in startups is brought to you by |
| 0:54.3 | LinkedIn Jobs. A business is only as strong as its people and every hire matters. Post your first |
| 1:00.0 | job for free at LinkedIn.com slash angel. Pre-newvo. Catch health conditions before they become crises |
| 1:06.7 | with the Pre-newvo full-body MRI scan. Get $300 off at Pre-newvo.com slash twist. And pilot. |
| 1:14.4 | Grow your business sustainably and operate more effectively. Pilot provides the most |
| 1:19.2 | reliable accounting CFO and tax services for startups and small businesses. Head to pilot.com slash |
| 1:25.0 | twist and get 20% off the first six months. Emily Melton is a managing partner and co-founder of |
| 1:33.1 | Threshhold investing primarily at the intersection of technology and healthcare. An active founding |
| 1:38.7 | member of AllRays and a three-cycle investor if I'm not mistaken. Welcome, Emily. |
| 1:44.8 | That's another way of saying old, right? That's for a while. No sage. I think we're going |
| 1:53.2 | with sage. We'll go with sage. I am thrilled to be here with you today. I'm delighted as well. |
| 2:00.0 | Okay, so tell me. Let's do the path to sage, the origin story. How did you |
| 2:08.7 | get your start in this field and what's been the road? I think you've heard me tell this before. |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Jason Calacanis, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Jason Calacanis and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2026.