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Nature Podcast

Ancient DNA reveals farming led to more human diseases

Nature Podcast

[email protected]

Science, News, Technology

4.4859 Ratings

🗓️ 9 July 2025

⏱️ 38 minutes

🧾️ Download transcript

Summary

00:48 The past 35,000 years of disease

Ancient DNA evidence shows that the advent of agriculture led to more infectious disease among humans, with pathogens from animals only showing up 6,500 years ago. The DNA, extracted from human teeth, shows the history of diseases present in Eurasia over tens of thousands of years. The approach used could be a powerful way to understand how illness has shaped humanity, but it is unable to detect some bacteria that enter the bloodstream at low concentrations or some viruses, so future work could seek to fill that gap.


Research Article: Sikora et al.

News: Animal diseases leapt to humans when we started keeping livestock


10:58 Research Highlights

DNA studies confirm that sardines were a major ingredient of the Roman Empire’s favourite fish sauce, and how analysis of animal manure identified global hotspots for antibiotic-resistance genes.


Research Highlight: Ancient DNA helps trace stinky Roman fish sauce to its source

Research Highlight: Poo of farm animals teems with drug-resistance genes


13:17 Using whale poo to study toxic algae in the Arctic

A 19-year experiment sampling bowhead whale faeces reveals a link between warming Arctic waters and increasing levels of toxic algae, researchers say. While climate change is expected to drive increases in the prevalence of harmful algal blooms, long-term data is lacking. To address this, a team worked with indigenous communities to collect and sample whale poo, showing that increases in algal toxins in the Arctic food chain are linked to rising ocean temperatures. The researchers suggest levels of these toxins need to be closely monitored to protect Arctic communities that depend on marine resources for food.


Research Article: Lefebvre et al.


24:06 Briefing Chat

An object from beyond our solar system has been spotted zipping past Jupiter, and evidence that Neanderthals created ‘fat factories’ to extract vital nutrients from animal bones.


Nature: Neanderthals boiled bones in ‘fat factories’ to enrich their lean diet

Nature: Rare find: interstellar visitor seen blazing through our Solar System


Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.


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Transcript

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0:00.0

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and use code Pod 10 for 10% of our professional membership categories.

0:31.7

Nature.

0:34.3

In an experiment.

0:35.1

Why is blight so far? Like, it sounds so simple. They had no idea. But now the data's... I find this not only refreshing, but at some level astounding.

0:49.5

Nature.

0:53.6

Welcome back to The Nature podcast.

0:56.6

This week, how ancient diseases shaped humanity.

1:00.6

And how whales excrement is helping researchers understand algal blooms.

1:06.3

I'm Nick Perchichelle.

1:07.5

And I'm Charmany Bundell.

1:25.8

Yeah. Take a pair to chichelle. And I'm Charmany Bundell. First up, an analysis of DNA from ancient microbes has shed light on some of the earliest human diseases and on what may have driven the first prehistoric

1:28.9

outbreaks. Reporter Anand Jagatia takes up the story. Diseases have undoubtedly shaped the course of

1:35.7

human history. From COVID-19 and malaria to the black death, pathogens have been infecting,

1:42.2

sickening and killing people for millennia. But since when, exactly?

1:47.9

One big question that we are trying to solve for many pathogens in particular is when in human history

1:54.7

or prehistory did they actually become human pathogens? This is Alexander Herbig from the Max Planck Institute for Evolutionary Anthropology.

2:04.5

They have certainly evolved from their ancestors, bacterial or viral,

...

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