Welcome to the Brain Health Revolution podcast with your hosts, Aisha and Dean Sharesai.

In this episode, we sat down with Dr. Hussein Yassine, who is an associate professor in the

Department of Medicine, Keck School of Medicine of the University of Southern California.

He directs the Yassine Lab, which specializes in how changes in lipid metabolism and

nutrition affect cognition and the risk of developing Alzheimer's disease.

The lab has an interest in studying how carrying the APOE4 allele, the strongest genetic risk

factor for developing Alzheimer's disease, affects lipid metabolism, the response to diet,

combining basic science, clinical trials, and brain imaging studies.

He directs the Roybal Alzheimer's disease research program focused on understanding

how obesity, diabetes, and vascular risk factors in Los Angeles Latin X population affect cognition

and Alzheimer's disease risk using longitudinal studies with cerebrospinal fluid and brain imaging

biomarkers.

He also runs the lipid clinic at the healthcare centers in East Los Angeles,

providing care for a large population of complex lipid and diabetes disorders that are referred from all over the Los Angeles County clinics.

It was an amazing conversation, and we hope you enjoy it as

much as we did. Thank you for joining us today. Well, Dr. Yassin, it's so wonderful to have you

here with us. Thank you so much for joining us. Of course, my pleasure. And thank you both Dean and

Ayesha for this invitation. Wonderful. We're both, as you know, neurologists and we do research.

I was the director of research education for Loma Linda for many years.

And then at Cedar Sinai, we were both the co-directors of brain health in Cedar Sinai.

And then back in Loma Linda as the directors of brain health and Alzheimer's prevention program.

But our singular focus has been on prevention and lifestyle.

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