5 • 716 Ratings
🗓️ 12 September 2019
⏱️ 17 minutes
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| 0:00.0 | Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen. |
| 0:06.9 | You can track me down on LinkedIn. You can also find me at reallife pharmacology.com or MedEd101.com |
| 0:16.1 | and hit the contact button there. And you can shoot me an email if you've got any questions, concerns, |
| 0:21.8 | looking for more information there. I try to respond to all the emails I get. I definitely do. |
| 0:28.2 | So you can find me there. With that, let's get into it today. I'm covering a cyclovir. |
| 0:35.1 | Brand name of this medication is Zoverax. And I'm really going to focus primarily on the |
| 0:41.9 | oral dosage form here comes as IV as well. I guess systemic drug in systemic circulation rather |
| 0:50.3 | than the topical acyclavir. So that's going to be my primary focus here. |
| 0:56.2 | So first off, getting into that mechanism of action, |
| 0:59.3 | how does this drug work? |
| 1:01.7 | Well, you've got to remember that it's used for viral infections, |
| 1:06.2 | and it's only used for certain viral infections. |
| 1:09.9 | Okay, so, you know, your common head cold, influenza, those type of viral infections, |
| 1:17.0 | this drug does not get used for that. |
| 1:20.0 | So it's important to remember that. |
| 1:22.8 | The primary uses I'll talk about after the mechanism here. |
| 1:26.4 | But how this drug works, it's actually transformed from its original state by the virus's own |
| 1:34.6 | thymidine kinase, and it gets converted to acyclovir monophosphate, and it continues to have phosphates added, |
| 1:46.1 | phosphate groups added to the drug |
| 1:48.3 | until it becomes acyclivir trifosate. |
| 1:51.9 | And that's really the active component |
| 1:55.8 | that prevents blocks that DNA production |
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