5 • 716 Ratings
🗓️ 12 September 2019
⏱️ 17 minutes
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0:00.0 | Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen. |
0:06.9 | You can track me down on LinkedIn. You can also find me at reallife pharmacology.com or MedEd101.com |
0:16.1 | and hit the contact button there. And you can shoot me an email if you've got any questions, concerns, |
0:21.8 | looking for more information there. I try to respond to all the emails I get. I definitely do. |
0:28.2 | So you can find me there. With that, let's get into it today. I'm covering a cyclovir. |
0:35.1 | Brand name of this medication is Zoverax. And I'm really going to focus primarily on the |
0:41.9 | oral dosage form here comes as IV as well. I guess systemic drug in systemic circulation rather |
0:50.3 | than the topical acyclavir. So that's going to be my primary focus here. |
0:56.2 | So first off, getting into that mechanism of action, |
0:59.3 | how does this drug work? |
1:01.7 | Well, you've got to remember that it's used for viral infections, |
1:06.2 | and it's only used for certain viral infections. |
1:09.9 | Okay, so, you know, your common head cold, influenza, those type of viral infections, |
1:17.0 | this drug does not get used for that. |
1:20.0 | So it's important to remember that. |
1:22.8 | The primary uses I'll talk about after the mechanism here. |
1:26.4 | But how this drug works, it's actually transformed from its original state by the virus's own |
1:34.6 | thymidine kinase, and it gets converted to acyclovir monophosphate, and it continues to have phosphates added, |
1:46.1 | phosphate groups added to the drug |
1:48.3 | until it becomes acyclivir trifosate. |
1:51.9 | And that's really the active component |
1:55.8 | that prevents blocks that DNA production |
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