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Cool Stuff Daily

A New Approach To Generalized Anxiety Disorder + We Were Wrong About Why Ice Is Slippery

Cool Stuff Daily

Reggie Risseeuw and Marques Pfaff

News, Tech News, Science, Society & Culture

4.6732 Ratings

🗓️ 12 September 2025

⏱️ 13 minutes

🧾️ Download transcript

Summary

A Single LSD Treatment Could Keep Anxiety At Bay for Months The Real Reason Ice is Slippery, Revealed After 200 years Secure your online data by visiting ⁠ExpressVPN.com/COOL⁠ to find out how you can get up to four extra months FREE. Contact the Show: [email protected] Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

Welcome to another edition of Cool Stuff Ride Home. My name's Marcus Path and coming up on this episode,

0:09.8

Generalized Anxiety Disorder, a crippling condition for many, but new research suggests relief

0:16.2

could come in a very unexpected form. Plus, for centuries, we thought we knew why ice was slippery.

0:23.1

Well, it turns out we had it all wrong. That plus this day in history coming up on cool stuff.

0:29.4

Turning once again to ZME science and author Mahai Andre. People suffering from generalized anxiety disorder or GAD often describe a constant feeling

0:41.2

of overwhelming, crippling worry. It's like a radio in your brain that's always catching static,

0:47.5

and it's so loud you can't focus on anything else. Now for decades, the primary tools to turn

0:53.5

down that static have been daily medications

0:55.8

and talk therapy. They sometimes work, but for roughly half of those who suffer, the noise

1:01.2

persists and there's no real treatment. A landmark study published in the Journal of the American

1:06.9

Medical Association suggests a radical new approach, turning the radio off and on again with LSD.

1:14.4

According to the study, a single medically supervised dose of lysurgic acid diethelamide, or LSD,

1:21.5

can provide profound and lasting relief from severe anxiety. In the most rigorous clinical trial of its kind,

1:29.5

a 100-microgram dose of the psychedelic compound silenced the debilitating worry of GAS for up to

1:36.8

12 weeks, offering a glimpse into what could be a revolutionary new chapter in mental health care.

1:42.9

Now, to be clear, generalized anxiety disorder is

1:45.7

not the feeling of worry you feel before a big presentation or some stressful event. It's a chronic

1:51.9

and debilitating condition characterized by what Dr. David Fifell, one of the studies investigators,

1:57.9

calls, quote, continuous worry, inability to relax, and all the physical manifestations,

2:03.6

racing heart rates and sweatiness, end quote.

2:06.6

It erodes your ability to work, maintain relationships, and simply enjoy your life.

2:11.6

And when conventional treatments don't work, patients are left with few options.

...

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