Could weight loss drugs make it harder to keep the pounds off in the long run? Live from the UK,

this is the Marketplace Morning Report from the BBC World Service. I'm Guy Kilty. Good morning.

Revolutionary weight loss jabs like Azenpick, Manjaro and Wagovi have flooded the market in the past

couple of years, helping millions of people shed excess pounds and creating a boom in the farmer industry. But a new UK study published in the British

Medical Journal says that while these injections can be effective initially, once users stop taking

them, they can regain their lost weight four times faster than those who stop conventional

dieting and exercising. The BBC's Nick Marsh has been looking into this. Hi Nick.

Hello Guy. So does the report say why people who've been taking the weight loss drugs

do put on the weight much more quickly? What it found was that even though these weight loss

shabs are incredibly effective at helping people lose weight,

basically suppresses your hunger by providing this hormone, GLP1,

even though they are incredibly effective at doing this, if you suddenly come off them,

it found that people were gaining, on average, 0.8 kilos a month compared to 0.1 kilos a

month if you were dieting and exercising and stopped doing that. Now, even though the study

didn't explicitly say why, there's lots of experts say that artificially producing this

hunger-suppressing hormone over long periods

of time in your body means that your body could produce less of its own natural GLP-1,

the hunger-suppressing hormone. And so when you come off the drugs, you're going to be even

hungrier than you were before you even went on them. The companies that make these drugs,

what have they said in response to this survey?

So there's a couple of main pharmaceutical companies that we're talking about,

Eli Lilly, an American company that makes Monjaro, Novo Nodiersk,

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