4.7 • 4.6K Ratings
🗓️ 9 September 2024
⏱️ 207 minutes
🧾️ Download transcript
Click on a timestamp to play from that location
0:00.0 | There's been a lot of controversy over the last few months. |
0:03.3 | The internet's been ablaze with speculation. |
0:05.9 | I think it's important to get it up top. |
0:08.6 | What is happening with the state of the Adenosine system research |
0:11.8 | within the first 90 minutes of the It accumulates with the number of hours that you're awake. So the longer you're awake the more |
0:26.4 | a denisine accumulates. It does many things in the brain and body. One of the most important things that it does is to give us the subjective experience of feeling |
0:36.7 | sleepy and the objective feeling of our body being fatigued, of feeling |
0:43.2 | literally heavier, requiring more energy to move ourselves. |
0:48.2 | When we sleep and when we allow ourselves to go into states of deep rest that are similar to sleep, we can talk about this. |
0:56.3 | The adenosine system is adjusted so that there's less effective adenosine circulating or bound to adenosine receptors. |
1:05.3 | Okay, so this sort of adenosine 101. There's a lot more to it, but that's sufficient |
1:10.8 | for what we need to talk about for now. |
1:14.0 | The drug, the most commonly used drug, |
1:18.0 | the drug we're using now, and that we're on right now, |
1:21.0 | caffeine, which is consumed by, |
1:23.1 | it's estimated more than 90% of the world's adult population, |
1:29.3 | effectively works by blocking the adenosine receptor. |
1:32.3 | There's some nuance there, but we can think of it that way for simplicity sake. |
1:36.0 | And in doing so, it prevents the sleepiness-inducing actions of adenosine. |
1:41.0 | However, when caffeine wears off, the adenosine that was around trying |
1:47.4 | to bind to those receptors is still around. In fact, it's accumulated even more, which at least partially explains the so-called caffeine crash or the dip in energy, |
1:58.8 | the fatigue that is that we experience maybe three or four hours after consuming caffeine. |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Chris Williamson, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Chris Williamson and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2025.