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🗓️ 3 February 2020
⏱️ 78 minutes
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The Convention on Psychotropic Substances was a 1971 United Nations treaty that placed strong restrictions on the use of psychedelic drugs — not only on personal use, but medical and scientific research as well. Along with restrictions placed by individual nations, it has been very difficult for scientists to study the effects of psychedelics on the brain, despite indications that they might have significant therapeutic potential. But this has gradually been changing, and researchers like Robin Carhart-Harris have begun to perform controlled experiments to see how psychedelics affect the brain, and what positive uses they might have. Robin and I talk about how psychedelics work, how they can help with conditions from addiction to depression, and how they can help people discover things about themselves.
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Robin Carhart-Harris received his Ph.D. in psychopharmacology from the University of Bristol. He is currently the Director of the Centre for Psychedelic Research in the Department of Brain Sciences at Imperial College London, and holds an honorary position at the University of Oxford. His research involves functional brain imaging studies with psilocybin (magic mushrooms), LSD, MDMA (ecstasy) and DMT (ayahuasca), plus a clinical trial of psilocybin for treatment-resistant depression.
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0:00.0 | Hello everyone and welcome to the Minescape Podcast. I'm your host Sean Carroll. |
0:04.8 | Back in 1747, Julian Afroy De La Metrie wrote an influential book called Man a Machine. |
0:11.8 | This is, I think, in the Enlightenment period in Europe, one of the first works to come |
0:17.2 | out strongly in favor of being an atheist. There were hints by various people that maybe |
0:22.8 | God wasn't all used cracked up to be, but still this was absolutely clear, man a machine, |
0:28.4 | but God didn't exist. We human beings are more like machines than embodied spirits. The |
0:34.5 | 18th century was a big time for machines in France and the rest of Europe, so this is a |
0:38.4 | vivid metaphor at the time. And De La Metrie was not one of the world's great philosophers, |
0:43.3 | but he was more like a pundit, I guess we would say, in these days. He had very vivid |
0:47.7 | metaphors and language and examples. He put his case in a very clear way for people to |
0:53.6 | understand. I remember one of the points that he made. I'm paraphrasing now his pen years |
0:57.9 | since I read it, but basically he was arguing against René Descartes' idea of mind-body |
1:03.5 | dualism. That a human being is a body, but then there's also a mind that is disembodied |
1:09.0 | and somehow they talk to each other and that makes the person. So De La Metrie didn't |
1:12.8 | buy this. He basically would say that the human being is a physical object and the mind |
1:18.4 | is emergent in our modern language. But the example he used was he says, look, when I |
1:22.8 | have had my cup of coffee or not had my cup of coffee, I'm a different person. Depending |
1:28.2 | on whether that's happened or not, how can you possibly believe that the mind is completely |
1:33.6 | separate from the body when it's perfectly clear that my mind is deeply affected by |
1:38.2 | what happens to my body? It's a very good point, really. And of course, the people who don't |
1:43.6 | believe him have answers to it, etc. But nevertheless, the example lingers in your mind. |
1:49.1 | These days, when we know even more about how the brain works, how the body works, how |
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