#50: How to read the medical literature like a journal editor

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.8 • 3.1K Ratings

🗓️ 31 July 2017

⏱️ 56 minutes

🔗️ Recording | iTunes | RSS

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Summary

Master this practical approach to reading the medical literature (*No statistics needed!) with expert tips from Dr. Christine Laine, Editor in Chief, Annals of Internal Medicine, and Dr. Darren Taichman, Executive Deputy Editor, Annals of Internal Medicine. They teach us what we should be reading, and detail their thought processes as they appraise an article. Topics covered include: Is 3 minute critical appraisal possible? What’s the deal with P-values? What are common sources of bias? How does the approach differ with clinical trials versus observational studies versus meta-analyses?

*Minimal statistics needed ; )

Full show notes available at http://thecurbsiders.com/podcast

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Time Stamps

00:00 Intro

01:13 Listener comment on Entresto

02:50 Picks of the week

09:36 Getting to know our guests

14:00 How to stay up on the medical literature

17:15 Three minute critical appraisal

19:15 Step 1: Assess the outcome being studied

20:50 Statistical versus clinical significance

22:33 Evaluating composite endpoints

24:47 Statistical power

28:58 Evaluating for bias

34:40 Recap of what we’ve learned so far

36:33 Is PICO useful?

39:01 Observational studies and bias

41:09 Evaluating a meta-analysis

46:05 Take home points

50:35 The Curbsiders recap the episode

53:02 Outro

Tags: literature, appraisal, meta, analysis, analyze, critical, read, medical, journal, study, randomized, observational, systematic, review, clinical, trial, assistant, care, education, doctor, family, foam, foamed, health, hospitalist, hospital, internal, internist, nurse, medicine, medical, primary, physician, resident, student

Transcript

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0:00.0	What what was the name of that journal again?
0:02.2	Eastern Yugoslavia journal of a five-basket weaving and
0:05.0	performance or apathy. Eastern Yugoslavia journal of five-basket weaving.
0:09.0	Are we going back to the loud typing bit, Stewart? I like it.
0:12.8	It's fantastic. It's a classic.
0:16.2	Little curbside or street for the old.
0:30.0	Welcome back to the curbsiders. Hello, Matt.
0:35.0	Hello, Stewart. Hello.
0:37.0	And Paul. And Paul. Paul, I'm not forgetting about you. Hello, Paul.
0:40.4	This is the internal medicine podcast that uses expert interviews to bring you
0:44.8	clinical pearls and practice changing knowledge. I'm Dr. Matthew Wato here
0:48.6	with my co-host, Dr. Stewart Brigham. Hello, Dr. Wato.
0:54.0	And Dr. Paul Williams. I'm betting if we tallyed up the number of times
0:58.7	we say hello in an episode, it has to be double digits.
1:05.2	Paul, do that. Paul has low blood sugar. We better burn through this one, Stewart.
1:11.5	Okay. I'd like to start off by reading a comment made by a listener on the website.
1:17.2	And I apologize to the listener. I don't have your, it was a, a farm D, but I do not
1:23.0	have his, his or her name in front of me, but they brought up a great point.
1:27.1	So recently we spoke with Dr. Eric Adler from University of California,
1:31.1	San Diego about heart failure. And we were speaking about the, the newer drug
1:35.3	and trestle, which is Valsartin, sec Cubitro, which I probably mispronounced.
1:40.8	And this person brought up the fact that on intresto, there's a 24 to 36 hour
	...

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