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The Curbsiders Internal Medicine Podcast

#496 Hotcakes: Cannabidiol (CBD)-induced liver injury, IV iron for HFrEF, bedtime BP meds, Carpal Tunnel Syndrome & RA, & Finerenone for HFpEF

The Curbsiders Internal Medicine Podcast

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.83.1K Ratings

🗓️ 25 August 2025

⏱️ 60 minutes

🧾️ Download transcript

Summary

Join us as we review recent practice-changing articles on cannabidiol (CBD)-induced liver injury, IV iron for HFrEF, bedtime administration of blood pressure meds, carpal tunnel syndrome & rheumatoid arthritis , & FDA approval of finerenone for HFpEF. Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Rahul Ganatra (@rbganatra), Nora Taranto (@norataranto) and Matt Watto (@doctorwatto).

Claim CME for this episode at curbsiders.vcuhealth.org!

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Credits

  • Written and Hosted by: Rahul Ganatra MD, MPH; Nora Taranto MD, Paul Williams, MD, FACP, Matthew Watto MD, FACP
  • Cover Art: Rahul Ganatra MD, MPH
  • Reviewer: Emi Okamoto, MD
  • Technical Production: Pod Paste
  • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Show Segments

  • Intro, disclaimer
  • CBD-induced liver injury
  • IV Iron in HFrEF
  • Bedtime administration of BP medications
  • Carpal tunnel syndrome and RA
  • FDA approves Finerenone for HFpEF
  • Outro

Sponsor:
Permanente

Want to join thousands of physicians who've made TPMG their career destination? Discover more at northerncalifornia.permanente.org


Transcript

Click on a timestamp to play from that location

0:00.0

Hey, before we get to the show, I wanted to remind you to check out our Patreon at patreon.com slash curbsiders.

0:06.7

If you haven't signed up yet, sign up now to get ad-free episodes, twice-monthly bonus episodes, and a whole bunch of other cool stuff at patreon.com slash curbsiders.

0:18.8

Hey, Paul, I burnt my pizza today.

0:23.5

Tell me more, Matt.

0:25.4

Yeah, it was a, it was a Hawaiian pizza, Paul.

0:28.5

So I think I should have cooked it at Aloha temperature.

0:33.7

That is truly awful.

0:35.1

And you should be filled with shame.

0:37.1

You know, I mean, puns are...

0:39.3

I'm not.

0:40.7

Yeah, you know, puns are often bad, but I enjoy them, Paul.

0:45.3

I think secretly you do as well, and we can all agree to that.

0:50.2

Paul, let's get to the show.

1:11.7

The Curbsiders podcast is for entertainment, education, and information purposes only, and the topics discussed should not be used solely a diagnosed, treat, cure, or prevent any diseases or conditions. For the more of the views and statements expressed on this podcast are solely those of those and should not be interpreted to reflect official policy or position of any entity. Aside from possibly cash like more hostile and affiliate outreach programs, if indeed there are any. In fact, there are none. Pretty much we are responsible if you screw up. You should always do your own homework and let us know when we're wrong.

1:20.9

Welcome back to the curbsiders.

1:26.9

I'm Dr. Matthew Frank Wado, here with my great friend and America's primary care physician. His, his mom tattoos that on his underwear, sews that in his underwear. Paul, is that, is that friends? You want to take that one again? No, I'm going to let it stand. I'm just bombing the whole intro. And, uh, if the audience can't tell, we haven't recorded in probably a month. And we're just, you know, working the kinks out. We're easing into it. How you doing? I'm good, Matt. How are you? I'm doing well. This is, it's hotcakes. I'm bombing. And, but we have two great co-hosts. And I'll let you introduce the show and tell everyone who they are and what we're going to do tonight.

1:46.0

Sure. We have two great co-hosts, and I'll let you introduce the show and tell everyone who they are and what we're going to do tonight.

2:04.1

Sure.

2:04.8

So I'll remind our audience, as we are generally the internal medicine podcast, and we typically use expert interviews to renew clinical pearls and practice changing knowledge.

2:11.8

But tonight, this is one of our renowned hot to cakes episodes where we review current literature for you, the listener, and let you know how we thought about it, what we thought about it, whether it is actionable stuff. And Matt, we are joined, of course, by two elite veteran members of the Curbsiders team, our resident epidemiologist, Dr. Rahulganacha, and freshly minted official hematologist,

2:32.9

oncologist. How would you like to be referred to Dr. Toronto? Actually, just oncologist. I don't think to call you hematologist, um, hematologist, oncologist?

2:34.3

How would you like to be referred to Dr. Toronto?

...

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