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The Curbsiders Internal Medicine Podcast

#479 Managing Treatment-Resistant Depression featuring Dr. Jessi Gold

The Curbsiders Internal Medicine Podcast

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.83.1K Ratings

🗓️ 14 April 2025

⏱️ 94 minutes

🧾️ Download transcript

Summary

Lead the way in depression management! We’re joined by Dr. Jessi Gold, a psychiatrist and mental health advocate, who provides essential pearls on ways to recognize the multifaceted nature of depression and similarly presenting medical conditions. We also discuss the complexities of treatment options including various medication options and therapies, and how to choose between these treatments.

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Show Segments

  • Intro
  • Case 1 from Kashlak
  • Medical conditions that can mimic depression
  • Diagnosis of depression
  • How to explain depression to family
  • Initial treatment options for depression
  • Case 2 from Kashlak
  • Suicide risk assessment
  • Trialing, augmenting, and tapering of medications
  • Pharmacogenetic testing
  • Alternate treatment options: TMS, ECT, ketamine, psilocybin, cannabis
  • Outro

Credits

  • Written and Produced by: Zoya Surani
  • Show Notes, Infographic, and Cover Art: Zoya Surani
  • Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
  • Reviewer: Sai Achi MD,MBA,FACP
  • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
  • Technical Production: PodPaste
  • Guest: Jessi Gold, MD

Disclosures

Dr. Gold reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures. 


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Transcript

Click on a timestamp to play from that location

0:00.0

Hey, before we get to the show, I wanted to remind you to check out our Patreon at patreon.com

0:05.7

slash curbsiders.

0:06.9

If you haven't signed up yet, sign up now to get ad-free episodes, twice-monthly bonus episodes,

0:12.1

and a whole bunch of other cool stuff at patreon.com slash curbsiders.

0:19.5

Hey, Paul, my sister was crying.

0:22.9

So I asked her if she was having a crisis.

0:31.2

No good?

0:32.3

No.

0:34.3

Crisis?

0:35.1

No, listen, I got the joke.

0:38.2

It's just, it's, it's not, it's not good.

0:41.0

All right, Paul.

0:41.5

What do you got?

0:42.8

Nothing.

0:43.6

Nothing.

0:44.1

Yeah, I'm sorry.

0:45.1

Just judgment for you.

0:50.2

The Curbsiders podcast is for entertainment, education, and information purposes only.

0:53.3

And the topics discuss should not be used solely a diagnosed, treat, cure, or prevent any diseases or conditions.

0:56.7

For the more of the views and statements expressed on this podcast are solely those of those and should not be interpreted to reflect official policy or position of any entity.

1:00.8

Aside from possibly, cash like more honest, and affiliate outreach programs.

1:03.1

If indeed, there are any.

...

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