#477 Hotcakes: Suzetrigine for acute pain, SGLT2i and PAD, Safety of Lowering LDL, Restrictive vs Liberal Transfusion Strategy in MI revisited

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.8 • 3.1K Ratings

🗓️ 31 March 2025

⏱️ 50 minutes

🔗️ Recording | iTunes | RSS

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Summary

Join us as we review recent practice-changing articles on suzetrigine for acute pain, the risk of PAD events from SGLT2 inhibitors, the safety of very low LDL, and the benefits of restrictive vs liberal transfusion strategies in acute MI with anemia. Fill your brain hole with a delicious stack of hotcakes! Featuring Rahul Ganatra (@rbganatra), Matt Watto (@doctorwatto), and special guest Molly Brett (Paul Williams got a break and took a much-needed vacation this week!).

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Credits

Written and Hosted by: Rahul Ganatra MD, MPH; Molly Brett MD, and Matthew Watto MD, FACP
Cover Art: Matthew Watto MD, FACP
Reviewer: Leah Witt, MD
Technical Production: Pod Paste
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

Show Segments

Intro, guest introduction, disclaimer
Cognitive safety of very low LDL Cholesterol
Suzetrigine for acute pain
Risk for amputation associated with SGLT2 inhibitors
Transfusion strategies in acute MI with anemia revisited
Outro

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Transcript

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0:00.0	Hey, before we get to the show, I wanted to remind you to check out our Patreon at patreon.com slash curbsiders.
0:06.7	If you haven't signed up yet, sign up now to get ad-free episodes, twice-monthly bonus episodes,
0:11.9	and a whole bunch of other cool stuff at patreon.com slash curbsiders.
0:18.9	Hey, Rahul.
0:20.6	Hmm? What if there were no
0:23.5	hypothetical questions?
0:27.5	I don't know.
0:29.2	What if?
0:31.5	That's it.
0:32.2	That was good fun.
0:34.9	Oh, man.
0:36.2	I feel like I walked into something.
0:41.6	Yeah. Oh, man. I feel like I walked into something. The Curbsiders podcast is for entertainment, education, and information purposes only, and the topics discussed should not be used solely to diagnose, treat, cure, or prevent any diseases or conditions.
0:48.0	For the more of the views and statements expressed on this podcast are solely those of those and should not be interpreted to reflect official policy or position of any entity aside Aside from, possibly, cash like moral, hostile, and affiliate outreach programs.
0:54.4	If indeed, there are any.
0:55.3	In fact, there are none.
0:56.2	Pretty much, we are responsible if you screw up.
0:57.4	You should always do your own homework and let us know when we're wrong.
1:06.5	Welcome back to the curbsiders.
1:07.9	I'm Dr. Matthew Frank Wado, here without America's primary care physician, Dr. Paul Nelson Williams.
1:14.3	But I have a great co-host, Dr. Rahul, how are you doing?
1:19.6	I'm doing great, Matt. How are you?
	...

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