#456: Prof. Glenn McConell – Glucose Uptake During Exercise & Muscle Insulin Sensitivity

Sigma Nutrition Radio

Danny Lennon

Sigma, Dietetics, Evidencebased, Nutrition, Training, Health & Fitness, Science, Diet, Fitness, Evidence, Bodybuilding, Health

4.8 • 626 Ratings

🗓️ 4 October 2022

⏱️ 63 minutes

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Summary

Exercise improves metabolic control both via increasing muscle glucose uptake during muscle contractions by insulin-independent mechanisms and by increasing skeletal muscle insulin sensitivity after physical activity. A reduction in skeletal muscle insulin sensitivity is an early event in the development of not only prediabetes, metabolic syndrome, and type 2 diabetes but is also associated with other conditions such as cardiovascular disease and some cancers.

One of the researchers that has been at the forefront of research in this area for many years is Professor Glenn McConell. In this episode we discuss glucose uptake during and after exercise, looking at both insulin-dependent and insulin-independent mechanisms. In addition we discuss the crucial importance of muscle insulin sensitivity and some important research breakthroughs on the topic.

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0:00.0	Hello and welcome to Sigma Nutrition Radio. My name is Danny Lennon and you are listening to episode 456 of the podcast. You are very
0:24.8	welcome. Today I'm going to be talking to Professor Glenn McConnell, who was Professor of
0:32.0	Exercise Metabolism at Victoria University based in Melbourne, Australia. He has more than 30 years of experience
0:39.8	in exercise metabolism research. He's an internationally recognized researcher in regard to
0:45.8	the regulation of muscle glucose uptake in both normal physiology as well as in diabetes.
0:52.2	And a lot of his research has focused on glucose metabolism and exercise.
0:57.0	And so this is included not only skeletal muscle glucose uptake during exercise as well as after,
1:04.0	but the increased insulin sensitivity that can come off the back of exercise.
1:10.0	And so we're going to discuss many of these topics today
1:12.5	and hopefully give you an insight into how his research has helped shape some of the field
1:19.2	related to glucose metabolism and exercise. Now along with this episode, because some of this
1:25.2	stuff can get quite detailed, you may be interested in getting
1:28.8	our detailed study notes, which we do for our podcast episodes for Sigma Nutrition Premium
1:35.3	subscribers. So if you are currently listening on our free feed, then you might be interested
1:40.7	in checking out what a Sigma Nutrition Premium subscription is. Like I said,
1:44.5	you get these detailed study notes, which are multiple pages and a beautiful PDF where you can
1:49.1	go and get not any diagrams and graphs, but breakdowns of certain topics, detailed explanations
1:55.6	of certain ideas, more background information, and essentially it serves as the perfect adjunct either to enhance your
2:02.5	understanding of what you've listened to or go back and revise the content at any time you wish.
2:08.9	In addition to that, you get bonus podcast episodes that are only available to Sigma Nutrition
2:13.8	Premium subscribers, you get transcripts to the podcast episodes, and you have the ability
2:18.6	to ask your questions directly, which we answer in exclusive podcasts. So if you want to check
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