#438: Diet, Brain Health & Cognitive Function

Sigma Nutrition Radio

Danny Lennon

Sigma, Dietetics, Evidencebased, Nutrition, Training, Health & Fitness, Science, Diet, Fitness, Evidence, Bodybuilding, Health

4.8 • 626 Ratings

🗓️ 17 May 2022

⏱️ 114 minutes

🔗️ Recording | iTunes | RSS

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Summary

Some cognitive decline is normal with age. However, more significant cognitive decline is primarily due to disease-induced dementias (such as Alzheimer’s Disease). It also results from neurodegenerative disorders and chronic, prolonged degeneration of our neuronal pathways and functions.

Drug discovery for dementias have been largely unsuccessful, leaving no good treatments for this collection of diseases. This had led to research examining areas that may aid in preventing (or more accurately, slowing) cognitive decline.

In this episode the Sigma team look at the published data on a variety of nutrients, foods and dietary patterns, including: vitamin D, omega-3 fatty acids, B vitamins, caffeine, flavanoids, coffee and green leafy vegetables.

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[00:02:01] Definitions
[00:08:40] What causes cognitive decline? Dementia? Mechanisms of ND pathogenesis.
[00:11:33] Why might nutrition play a role?
[00:18:18] Dietary patterns
[00:26:30] Diet interaction with APOE genotype
[00:31:18] Alcohol
[00:36:36] Polyphenols - mechanisms
[00:43:05] Coffee & Caffeine
[00:45:03] Flavanoids
[00:51:04] Vitamin D
[01:04:22] Omega 3 fatty acids
[01:21:42] B vitamins & green leafy veg
[01:30:35] Vitamin E
[01:38:24] How to assess cognitive health in ageing intervention studies
[01:45:28] Concluding thoughts

Show notes to this episode

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Transcript

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0:00.0	Hello and welcome to the podcast. This is Danny Lennon, and you're very welcome to Sigma Nutrition
0:05.3	Radio, the podcast where you get to hear detailed nuanced discussions about nutrition science
0:10.4	completely free of sensationalist, biased or pseudo-scientific preaching about a particular diet.
0:16.9	Rather, we focus on coming to fair conclusions based on the principles of evidence-based practice
0:21.8	and scientific inquiry. As you're hearing this message, that means you're listening on our
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0:39.9	So if you want more details on that, then just stay listening at the end of this episode.
0:44.0	Or right now, you can go and check out the details at sigmautrition.com or just click the link in the
0:49.6	description box of this episode. Your support is what makes it possible for us to continue to produce the
0:55.8	content that we do. And so with that, let's dive into this episode.
1:18.6	Thank you. Hello and welcome to another episode of Sigma Nutrition Radio.
1:22.3	This is episode 438 of the podcast.
1:26.0	I am Danny Lennon and I am here with Alan Flanagan and New Gaspel.
1:27.9	And today we're going to be talking all about diet and cognitive function, cognitive decline, neurodegenerative disease, and anything related to
1:35.9	these topics. So let's dive into it from at the very start. I mean, the best way as we usually do
1:41.9	is to lead off with some definitions of some
1:44.2	key terms that will be coming up throughout the rest of this conversation. And I'll maybe start
1:48.8	here with you, Neve, given as, as we'll talk about throughout this conversation, you have a number
1:54.4	of publications in this area. And so when we're talking about things like cognitive function
2:00.2	and then cognitive decline,
	...

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