#435: Fasting & Longevity – Does the Evidence Match the Hype?

Sigma Nutrition Radio

Danny Lennon

Sigma, Dietetics, Evidencebased, Nutrition, Training, Health & Fitness, Science, Diet, Fitness, Evidence, Bodybuilding, Health

4.8 • 626 Ratings

🗓️ 26 April 2022

⏱️ 86 minutes

🔗️ Recording | iTunes | RSS

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Summary

Current discussions relating to health focus on longevity. This may include some who look at lifespan extension, some who talk of delaying or “treating” ageing or those who focus on reducing morbidity within the parameters of normal lifespan.

One propsed intervention that has garnered a lot of excitement, owing to some interesting research, is the potential use of fasting to increase longevity and/or healthspan. Within this broad category, various different dietary interventions have been suggested, including various forms of intermittent fasting, time-restricted eating, dietary restriction of certain nutritients, calorie restriction or a “fasting-mimicking” diet.

But what does the current evidence tell us? Does the evidence actually match the hype? In this episode Dr. Niamh Aspell, Alan Flanagan and Danny Lennon discuss some of the data on fasting and longevity.

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0:00.0	Hello and welcome to the podcast. This is Danny Lennon, and you're very welcome to
0:18.2	Sigma Nutrition Radio, the podcast where you get to hear detailed
0:21.3	nuanced discussions about nutrition science, completely free of sensationalist, biased, or
0:27.3	pseudo-scientific preaching about a particular diet. Rather, we focus on coming to fair conclusions
0:32.5	based on the principles of evidence-based practice and scientific inquiry. As you're hearing this message,
0:38.8	that means you're listening on our public feed of the podcast. If you want to get supplementary
0:43.7	material that's going to enhance your learning, then you may be interested in subscribing to
0:47.9	our private premium feed, Sigma Nutrition Premium, with a bunch of cool features. So if you want more details on that, then just stay listening at the end of this episode.
0:57.8	Or right now, you can go and check out the details at sigmautrition.com or just click the
1:02.6	link in the description box of this episode.
1:05.5	Your support is what makes it possible for us to continue to produce the content that we do.
1:12.6	And so with that, let's dive into this episode. Hello and welcome to Sigma Nutrition Radio. My name is Danny Lennon. I'm here
1:22.9	with Alan Flanagan and Neve Aspel. And today we're going to be talking all about fasting and longevity.
1:28.3	A lot to unpack within this. And for those of you who follow our content regularly,
1:32.5	you will have seen a Sigma statement appear on the website in relation to this issue.
1:37.3	But there's a lot to unpick in some of the things that were raised. So hopefully we're going
1:41.4	to dive through some of that today. With this topic
1:45.0	of longevity and particularly any nutritional intervention that is aimed at it, I suppose the
1:50.6	origins of this typically have been in the form of things like caloric restriction and looking
1:56.0	at that impact on lifespan, or at least that was the initial emerging idea around the longevity slash anti-aging
2:03.7	community of looking at some of this data that originated in yeast and maybe in some other places
2:08.5	that we'll talk about of increasing lifespan. But of course, now in other areas, and particularly
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