#427 Kittleson Rules Amyloidosis

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.8 • 3.1K Ratings

🗓️ 19 February 2024

⏱️ 68 minutes

🔗️ Recording | iTunes | RSS

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Summary

The clinical picture of an underrecognized disease

Amyloidosis demystified. Learn the clinical clues that suggest possible amyloidosis and how to order the correct tests to diagnose this disease. We are joined by Dr. Michelle Kittleson who shows us the ropes of treating fibril accumulation, @MKittlesonMD (Cedars Sinai).

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Show Segments

Introduction
Case Presentation: Mr. Smith
Differential Diagnosis of Heart Failure with Preserved Ejection Fraction
Understanding Amyloidosis
Clinical Clues and Red Flags for Amyloidosis
Physical Examination Findings
Workup for Amyloidosis
Treatment Options
AL Amyloidosis and Hematologist's Role
ATTR Amyloidosis and Cardiologist's Role
Other Therapies for TTR Amyloidosis
Therapy on the Horizon
Cost and Access to Tafamidis
Alternative Therapies and Supplements
Monitoring and Side Effects of Tafamidis
Symptomatic Management and Anticoagulation
Take Home Points

Credits

Written and Produced by; Deborah Gorth, MD, PhD
Infographic and Cover Art: Meryl Gorth, RD, MPH and Deborah Gorth, MD, PhD
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Sai S. Achi MD MBA
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Michelle Kittleson, MD, PhD

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Transcript

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0:00.0	Hey listeners it's 2024 and we are so excited for everything ahead this year.
0:05.5	If you haven't done so already make sure to check out our Patreon at
0:09.1	Patreon dot com slash curbsideers where you can get access to bonus episodes we've already
0:13.9	released 18 of them and they come out twice a month plus you can get access to
0:18.0	add free episodes and our private discord server to hang out with other members of
0:22.4	the cashlack community.
0:23.7	That's Patreon.com slash curbsideers.
0:29.2	I want to tell you a little story Paul.
0:30.7	This is kind of sad.
0:32.0	It's a little dark. Oh no. All right. So Paul recently a family
0:36.0	a member of mine passed away in the hospital. He had a heart problem. You know, we're talking
0:40.9	about cardiomyopathy today and Paul we needed to perform a blood
0:46.0	transfusion in order to save this person and unfortunately none of us knew his blood type
0:51.0	and as he was dying Paul he kept out screaming be positive but you know
0:57.3	Paul it's just so hard without him.
1:00.3	Yeah I've heard variations of that joke. It's solid.
1:03.6	Yeah, yeah. Yeah, I've been, what did you find?
1:07.6	So I found an entire page. I'm not going to credit it because it's awful.
1:10.7	Um, of puns that I don't understand and there's some cardiology puns. So,
1:15.4	dating a heart surgeon can be a rhythmantic.
1:18.5	That's the joke. My cardiology professor likes to keep an aorta diary.
1:26.0	I need help.
	...

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