#415: Prof. Bruce Neal – Can Salt Substitutes Reduce Cardiac Events & Death?

Sigma Nutrition Radio

Danny Lennon

Sigma, Dietetics, Evidencebased, Nutrition, Training, Health & Fitness, Science, Diet, Fitness, Evidence, Bodybuilding, Health

4.8 • 626 Ratings

🗓️ 30 November 2021

⏱️ 46 minutes

🔗️ Recording | iTunes | RSS

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Summary

Bruce Neal is Executive Director at The George Institute for Global Health Australia; and Professor of Medicine, UNSW Sydney.

Prof Neal is a UK-trained physician who has 25 years’ experience in clinical, epidemiological, and public health research with a focus on heart disease, stroke and diabetes. Bruce has a longstanding interest in high blood pressure and diabetes and the potential for both clinical interventions and changes in the food supply to deliver health gains. His work has been characterised by its focus on collaboration, quantitation, translation and impact.

He holds professorial appointments at UNSW Sydney, Imperial College London, and an honorary appointment at the University of Sydney. He has published some 450 scientific papers and since 2016 has been identified by Thomson Reuters as one of ‘The World’s Most Influential Scientific Minds’, an acknowledgement provided to just a few thousand researchers across all disciplines, worldwide.

He has particular expertise in the conduct of large-scale clinical trials addressing cardiovascular disease but has also done a significant body of work addressing food policy issues related to sugars, fats, portion size and food labelling.

Find the show notes at sigmanutrition.com/episode415/

Transcript

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0:00.0	Hello and welcome to Sigma Nutrition Radio. I am your host, Danny Lennon. This is episode 415 of the podcast. You are very welcome.
0:25.7	Thank you to everyone who has had kind words to say about last week's episode where we went quite in-depth
0:32.2	and down the rabbit hole of looking at machine learning and data science and how that may apply to nutrition research going
0:39.0	forward. So a big, deep episode. And thank you for everyone who made their way through all of that.
0:45.4	And hopefully you enjoyed that discussion. And we welcome kind of further comments and questions.
0:50.3	So that was episode 414 of the podcast. Today we are going to be talking with Professor Bruce Neal,
0:57.9	who is the executive director at the George Institute for Global Health Australia, as well as being
1:03.0	Professor of Medicine at UNSW Sydney. Professor Neal has been involved in a variety of different clinical interventions over the years
1:12.9	with a particular interest in things like blood pressure and diabetes, but his work spans
1:18.4	well beyond that for several decades now. And he has particular expertise in conducting
1:24.0	large-scale clinical trials that look at things related to cardiovascular disease in particular.
1:31.2	Now, recently, he has shifted that towards a kind of a nutritional stand
1:35.2	and looking at how can we actually roll out maybe large-scale clinical trial styles
1:40.7	that we typically see in biomedical research and apply that to kind of nutrition questions.
1:46.9	And so this year, he was the lead author on a huge study that came out in the New England Journal
1:53.0	of Medicine, titled The Effect of Salt Substitution on Cardiovascular Events and Death,
1:57.4	or the SAS trial. And this quay made quite a splash when it was published for a number
2:03.8	of reasons, which will probably become clear as we start discussing it. And so I'm really, really
2:08.1	delighted to talk to Professor Neal about this particular study, and hopefully we'll get into
2:13.4	some of the details of that and then the implications of them. Of course, if you're a regular
2:18.3	listener, you will know we did an episode on salt, sodium and health back in episode 375 of the
2:24.9	podcast, where Alan and I went into a bit of detail on the nutritional epidemiology in this area,
	...

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