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Plenary Session

4.63 - ASCO22 - DYNAMIC - Can CT DNA Allow us to Give Less Chemo in Stage II Colon Cancer

Plenary Session

Vinay Prasad, MD MPH

Health, Medicine, Policy, Oncology, Science & Medicine

4.7789 Ratings

🗓️ 5 June 2022

⏱️ 36 minutes

🧾️ Download transcript

Summary

The second paper from #ASCO2022 #ASCO22 that I break down This is one of the most technical papers I breakdown on the channel CT DNA used to omit chemo in Stage II colon cancer Read the book Malignant if you learn from this Watch the YouTube Figures https://youtu.be/QxOBIi7I2BU

Transcript

Click on a timestamp to play from that location

0:00.0

Welcome to the channel. As promised, this is plenary session. Asco updates video edition.

0:06.0

I'm going to be talking about the dynamic study circulating tumor DNA and adjuvant stage 2 colon cancer, and this is by popular request.

0:13.0

Now first of all, if you're listening to this on the audio feed plenary session, I encourage you to stop what you're doing right now and get over to YouTube, get on the video feed.

0:21.6

I've got so many visuals, I've got slides, this is really a full lecture experience.

0:26.6

You're not going to want to listen to it just on audio.

0:29.6

You're not going to get the most from it.

0:30.6

So I encourage you to go over to the video feed.

0:32.6

We'll come back to the audio, don't you worry, on the plenary session feed.

0:35.6

Next point.

0:42.9

On this channel in plenary session, we've talked about so many studies, from historical control arms to poor control arm quality and randomized studies, post-protocol therapy, crossover.

0:48.1

These can be tricky.

0:49.9

This particular study dynamic is the most tricky of all of them.

0:53.4

I mean, we're talking about a biomarker used to omit chemotherapy.

0:57.0

This is, I think, the highest level of sophistication in study methodology, and it's going

1:03.3

to take a lot to understand it.

1:04.5

So, if you don't get it all the first time, watch the video again.

1:09.5

If you don't get it all the second time, sleep on it again. If you don't get it all the second time,

1:11.2

sleep on it, think about it, read the paper, return to the video. I hope that this will be

1:16.5

instructive to you and that this will actually be something novel and informative, unlike a lot of

1:21.0

the things I hear. All right, let's turn to a dynamic. This is the big, big talk of the town.

1:26.7

I see everyone on Twitter praising dynamic,

1:28.9

and they say, wow, isn't it wonderful that we finally have a blood-based test that allows us to

...

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