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Plenary Session

4.61 - How CDC's Vaccine Safety Missed Cases Of Myocarditis

Plenary Session

Vinay Prasad, MD MPH

Health, Medicine, Policy, Oncology, Science & Medicine

4.7789 Ratings

🗓️ 27 May 2022

⏱️ 55 minutes

🧾️ Download transcript

Summary

I am joined by Dr. Katie Sharff, infectious disease doc, to discuss two of her papers on myocarditis after COVID-19 vaccination. https://doi.org/10.1016/j.amjcard.2022.02.039 https://doi.org/10.1101/2021.12.21.21268209

Transcript

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0:00.0

I'm back in plenary session, virtual edition. I'm joined by Katie Sharf. Dr. Sharf is an infectious

0:07.5

disease expert. She's an ID doctor at Kaiser Permanente Northwest in Portland, Oregon. She's the chief of

0:12.7

ID. She's also the author of two really interesting papers that we're going to walk through and talk

0:17.0

about some of the complexity with methodology. I just want to read the title and then the conclusion, and then I'll turn it over to you, Dr. Sharp,

0:23.3

the title of the papers, so people get a sense of what we're going to talk about.

0:26.6

Risk of myoparocarditis following COVID-19 mRNA vaccination in a large integrated health

0:31.8

system, a comparison of completeness and timeliness of two methods.

0:35.7

And the next one.

0:37.0

Surveillance of myopacarditis

0:38.4

following COVID-19 booster dose vaccination in a large integrated health system. And I will just read

0:42.9

the conclusion, which I think will point us what we're going to talk about. We identified

0:47.8

additional valid cases of myopacarditis following an MRNA vaccination that would be missed

0:51.9

by the VSD search algorithm, which depends on select hospital discharge diagnosis codes.

0:56.8

The true incidence of myoporacarditis is markedly higher than the incidents reported to advisory

1:00.6

committees. The VSD should validate its search algorithm.

1:03.7

And then the other one concludes, we identified a rate of 9.1 cases of myoporocarditis

1:08.0

per 100,000 COVID-19 booster doses, which is higher than prior estimates

1:11.8

reported by VAERS. Dr. Sharf, thanks so much for doing this. Pleasure to talk to you.

1:16.5

Thanks for having me. Nice to see you. It's nice to see you. And I guess we should disclose,

1:20.4

we're both graduates of University of Chicago Medical School, Pritzker School of Medicine. A great

1:24.8

place. I enjoyed my time there. That's right, although I didn't know you

1:28.1

in medical school. We didn't. Well, I knew of you, but I don't think we had time. Yeah, I didn't have

...

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