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Plenary Session

4.11 CheckMate 274, PARADIGM-HF/Ernesto, POLO, & an AI Approach to Reducing Knee Pain

Plenary Session

Vinay Prasad, MD MPH

Health, Medicine, Policy, Oncology, Science & Medicine

4.7789 Ratings

🗓️ 31 July 2021

⏱️ 54 minutes

🧾️ Download transcript

Summary

Today's episode is a compilation of a few short monologues. We provide an oncologist's evidence-based medicine perspective on four papers: CheckMate 274, adjuvant nivolumab in urothelial cancer; PARADIGM-HF/Entresto; the POLO trial, olaparib in pancreas cancer; and the paper "An algorithmic approach to reducing unexplained pain disparities in underserved populations". CheckMate 274: doi.org/10.1056/NEJMoa2034442 PARADIGM-HF: doi.org/10.1056/nejmoa1409077 POLO: doi.org/10.1056/NEJMoa1903387 Knee pain: doi.org/10.1038/s41591-020-01192-7 Back us on Patreon! www.patreon.com/plenarysession Check out our YouTube channel: www.youtube.com/channel/UCUibd0E2kdF9N9e-EmIbUew

Transcript

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0:00.0

Welcome to Plenary Session.

0:07.9

I'm Vinay Prasad. I'm an associate professor with University of California, San Francisco.

0:11.9

I'm a practicing he-mong doctor, and my interests are medicine, oncology, and health policy.

0:16.4

And that's what you're going to get on Plenary Session.

0:21.6

This is season four, hashtag zero COVID.

0:24.6

It's zero COVID because we're not going to talk about COVID.

0:26.6

We're back, oncology, medicine, health policy.

0:29.6

We've got a lot in store for you.

0:33.6

But first, a plug.

0:34.6

If you like this podcast, leave us a rating or write us a review. It helps new listeners find the show. You can follow us on Twitter at Plenary underscore Session. You can email us at plenary session podcast at gmail.com. Give us your suggestions on what we should be covering. And we got a new YouTube channel, Vinay Prasad, MDMPH. Follow us on YouTube. I'm putting up a 10-part series on reading and interpreting cancer clinical trials.

0:57.6

You'll want to watch it there.

1:00.3

And if you really love this show, you can back us on Patreon.com.

1:04.1

Patreon backers get access to slides for lectures I give on plenary session.

1:08.3

And with that, let's start the show.

1:10.7

Dr. Vanai Prasad here, University of California,

1:13.3

San Francisco. I'm back, new video, checkmate 274. You've asked me to comment on it. So I took a

1:18.6

look at this publication, adjuvant nivit nivolumab and urethel carcinoma. Here are my thoughts.

1:23.3

I put together a few of them for you. Let me show you the paper. Here it is, New England journal paper.

1:28.3

Means it's got to be good, right?

1:29.8

Adjuvant nevolumab versus placebo and muscle invasive urethel carcinoma.

1:33.9

And here they include bladder cancer, about three quarters, and one quarter upper track

1:37.7

disease.

...

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