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Age Less / Live More

389: How to Live Forever with David Sinclair, PH.D.

Age Less / Live More

Lucas Rockwood

Love, Detox, Food, Yogabody, Pranayama, Vegan, Selfimprovement, Self-improvement, Relationships, Meditation, Breathing, Education, Emotions, Mental, Vegetarian, Inspiring, Leader, Balance, Motivating, Weightloss, Flexibility, Habits, Health, Motivation, Yoga, Nutrition

4.81.1K Ratings

🗓️ 12 December 2019

⏱️ 38 minutes

🧾️ Download transcript

Summary

I’ve set a personal goal to live to be 122, and I specifically chose this number because it seems like a stretch but also totally within the realm of reasonable given my age and the advances in science. My children, I’m almost certain, will easily surpass my age simply because they have even more time for science to make it possible. So if 80 is the new 50, what does that mean for our hair, teeth, and liver? What choices should we make now to extend not just our lifespan but our healthspan too?

My guest on this week’s show is a thought leader on longevity, and he’ll share his latest research from Harvard.

Listen & Learn:

  • How metformin, resveratrol, and NAD might be the ultimate pill stack for longevity we know of
  • Why it’s important to get hungry
  • Why you need to exercise to the point of breathlessness
  • How 20% of your health is genetic, the other 80% is up for grabs
  • How your choices today play out in your healthspan in the future

Links & Resources:

About Our Guest
David A. Sinclair, Ph.D. is a Professor in the Department of Genetics at Harvard Medical School and co-director of the Paul F. Glenn Center for the Biological Mechanisms of Aging. He is best known for his work on understanding why we age and how to slow its effects. He’s the author of a new book, Lifespan, found on Amazon or at his site.

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Transcript

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0:00.0

I set a goal for myself to live to be 122 and I pick the number because it's big

0:08.9

enough that it feels like a stretch it feels like a challenge but it's small enough

0:12.2

that I feel like it's very

0:13.6

realistic I really feel like I can get there and I really I like I like to set myself up

0:18.2

for wins so let's see how I do I think the real question the bigger challenge that

0:22.4

I feel and I mean this honestly is can I get to

0:24.5

122 with all my faculties in order that seems like the much bigger challenge at this

0:29.6

point I have three children I'm almost certain all of them based on the breakthroughs in medical science.

0:35.0

I think all of them will make it to over a hundred years of age.

0:39.0

What that means is there's a big shift in perspectives that all of us need to make in how we think about

0:45.7

aging, how we treat aging, and how we treat our bodies and our brains as we go

0:50.4

through life. You know if you look down at your sneakers I'm looking at

0:53.0

mine right now I'm hoping they last for another three months but if I needed

0:56.6

them if I was expecting them to last for another three four years three four

1:00.8

decades I'd have to do things really differently. So when I look at my

1:04.6

hair, when I look at my skin, my teeth, when I think about my mental capacity, my

1:09.2

brain, my cognition, I'm thinking about things with that number in mind and thinking, what can I really do to maximize not just my lifespan but my health span?

1:19.0

How can I live a life that's long but also young in terms of how I can behave and that's a big challenge

1:26.0

and that's something that I've been thinking about lately. My guest on this week's show

1:29.8

is David Sinclair, Harvard Medical School researcher.

1:33.5

There's a lot of work with genetics and the epigenome.

1:36.4

If you think of his analogy, which I really like,

...

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