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The Peter Attia Drive

#319 ‒ Peter's key takeaways on liver health, heart rate variability, AI in medicine, klotho, and lactate metabolism | Quarterly Podcast Summary #2

The Peter Attia Drive

Peter Attia, MD

Health & Fitness, Medicine, Fitness

4.77.3K Ratings

🗓️ 30 September 2024

⏱️ 28 minutes

🧾️ Download transcript

Summary

View the Show Notes Page for This Episode

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In this quarterly podcast summary (QPS) episode, Peter summarizes his biggest takeaways from the last three months of guest interviews on the podcast. Peter shares key insights from each episode, covering diverse topics such as liver health with Julia Wattacheril, heart rate variability with Joel Jamieson, artificial intelligence with Zak Kohane, klotho for brain health with Dena Dubal, and lactate and lactate metabolism with George Brooks. Additionally, Peter shares any personal behavioral adjustments or modifications to his patient care practices that have arisen from these engaging discussions.

If you’re not a subscriber and are listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or our website at the episode #319 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here.

We discuss:

  • Overview of topics, and the positive feedback on the quarterly podcast summary format [2:00];
  • Julia Wattacheril episode: liver health and disease [4:00];
  • Noninvasive methods to diagnose liver conditions, and how to manage and improve liver health [16:00];
  • Joel Jamieson episode: heart rate variability (HRV) for training and health [27:15];
  • Practical tools for measuring HRV and how it informs training and recovery decisions [37:00];
  • Zak Kohane episode: artificial intelligence and medicine [47:15];
  • The current role of AI in medicine and how it could revolutionize medicine in the future [53:45];
  • The limitations and concerns pertaining to AI [1:00:15];
  • Dena Dubal episode: the potential benefits of klotho for brain health [1:05:00];
  • Animal studies on klotho and brain health [1:11:00];
  • Genetics-based variations in klotho levels in humans and their impact on cognition, disease risk, and longevity [1:14:15];
  • Testing klotho levels, the significance of the KL-VS variant, the role of exercise in increasing klotho, and more [1:17:30];
  • The potential of klotho as a treatment for cognitive decline and Alzheimer's disease [1:23:15];
  • George Brooks episode: a new paradigm to think about lactate and lactate metabolism [1:27:45];
  • The potential for lactate infusions to aid in brain recovery following a head injury [1:34:00];
  • The relationship between lactate and cancer, and the impact of exercise on lactate levels and cancer risk [1:36:30]; and
  • More.

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Transcript

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0:00.0

Hey everyone welcome to a sneak peek ask Ask Me Anything, or AMA episode of the Drive Podcast.

0:16.0

I'm your host, Peter Attia.

0:17.7

At the end of this short episode, I'll explain how you can access the AMA episodes in full,

0:22.3

along with a ton of other membership benefits we've created.

0:25.4

Or you can learn more now by going to Peteratia MD.com forward slash subscribe.

0:31.0

So without further delay, here's today's sneak peek of the Ask Me Anything episode.

0:37.0

Welcome to another special AMA episode of The Drive.

0:43.0

Today's episode will be the second of what we're now calling the quarterly podcast summary.

0:48.0

We did the first episode of this back in June and the feedback was overwhelmingly positive. In fact, I don't think we've ever received

0:55.6

more feedback on the day of a podcast release than we did for the quarterly podcast summary number one.

1:01.6

So it's no surprise that we're going to bring this back and continue to do it because again people seem to really like this and quite frankly it's a lot of fun for me.

1:10.0

These quarterly podcast summaries will look back at recent episodes

1:13.8

released typically over the last quarter and I'll discuss what I learned from

1:17.9

the interview and what I think for some of the most important insights as well

1:21.5

as any changes in my behavior or thinking that resulted and Joel Jameson, Zach Kohani, Dina DuBall, and George Brooks.

1:34.9

Throughout this, we speak on topics such as liver health, heart rate

1:38.6

variability, the emergence of AI and its potential impact on medicine, the gene and protein clotho in its relationship

1:47.0

to Alzheimer's disease and its potential to treat these conditions, and all things related to lactate.

1:55.0

If you were a subscriber and would like to watch the full video of this

1:59.0

podcast you can find it on the show notes page.

2:01.0

If you're not a subscriber, you can watch a sneak

2:04.1

peek of the video on our YouTube page. So without further delay, I hope you enjoy

...

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