4.8 • 2.5K Ratings
🗓️ 1 October 2025
⏱️ 88 minutes
🧾️ Download transcript
In this episode, we’re cutting through the noise around strength, longevity, and weight loss with Dr. Gabrielle Lyon, a physician and founder of the muscle-centric medicine movement.
If you’ve ever wondered how to train for long-term health, this is your practical, science-backed guide. We dive into why building and maintaining muscle is essential not just for performance or appearance but for your metabolic health, brain function, immune system, and resilience as you age.
We cover:
💪 Why muscle is the organ of longevity and how it protects against chronic disease
🥗 What a muscle-centric plate looks like
🧠 How muscle influences your mood, memory, and brain health
🏋️♀️ The minimum effective dose of resistance training for busy lives
Plus, Dr. Lyon answers your biggest questions about GLP-1s, sarcopenia, protein, supplements, and how men and women should train differently as they age.
If you’re in your 30s, 40s, or beyond and haven’t prioritised muscle this conversation might just change your health trajectory.
Dr. Gabrielle Lyon is an accomplished physician and the New York Times bestselling author of FOREVER STRONG: A New, Science-Based Strategy for Aging Well.
Dr. Lyon's educational and research background includes dual clinical fellowships in geriatrics and nutritional sciences at Washington University, along with undergraduate training in nutritional sciences at the University of Illinois. A highly sought-after educator and consultant, she is an authority in the practical application of protein types and levels for health, performance, aging, and disease prevention. You can find out more from Dr Lyon here at https://drgabriellelyon.com/
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| 0:00.0 | If you've ever wondered what organ is most important for longevity, my guest today will say |
| 0:06.9 | unequivocally that it is about your muscle. And we're going to talk today about how you can |
| 0:12.3 | support your muscle health for a longer, stronger life. Hi, I'm Dr. Rupi. I'm a medical doctor and nutritionist. And when I suffered a heart |
| 0:24.0 | condition years ago, I was able to reverse it with diet and lifestyle. This opened up my eyes |
| 0:29.9 | to the world of food as medicine to improve our health. On this podcast, I discuss ways in which you |
| 0:36.9 | can use nutrition and lifestyle to improve |
| 0:39.4 | your own well-being every day. I speak with expert guests and we lean into the science, |
| 0:45.1 | but whilst making it as practical and as easy as possible so you can take steps to change your |
| 0:50.6 | life today. Welcome to the Doctor's Kitchen podcast. |
| 1:00.5 | Thank you. to change your life today. Welcome to the Doctor's Kitchen podcast. In today's episode, we're going to be cutting through the noise around strength and longevity and weight loss with Dr. Gabriel Lyme. |
| 1:06.8 | She's a physician and founder of the muscle-centric medicine movement, as I now put it. |
| 1:13.1 | If you've ever wondered how to train for long-term health, this is going to be a practical science-backed guide. |
| 1:19.7 | We're going to dive into why building and maintaining muscle is essential, not just for performance or appearance, but also for your metabolic health, your brain |
| 1:29.1 | function, your immune system and resilience as you age. As you're going to learn, your muscle is |
| 1:35.4 | an endocrine ormond. It is secreting hormones into your bloodstream where you have receptors |
| 1:41.3 | for things like myokines around your body, including in your brain, |
| 1:45.3 | your heart, your liver. It's super, super important. So we're going to cover why Dr. Lyon |
| 1:51.1 | believes that muscle is the organ of longevity and how it protects against chronic disease. |
| 1:58.1 | What a muscle-centric plate looks like. Yes, even for plant-focused diets as well, |
| 2:03.7 | what a muscle-centric activity looks like, how muscle influences your memory and brain health, |
| 2:10.2 | and the effective dosage for resistance training, even for people with busy lives like myself as a parent of a newborn as |
| 2:20.1 | well. We also talk to Dr. Lyne about some of the biggest questions that we've had about |
... |
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