#277 ‒ Food allergies: causes, prevention, and treatment with immunotherapy | Kari Nadeau, M.D., Ph.D.

The Peter Attia Drive

Peter Attia, MD

Health & Fitness, Medicine, Fitness

4.7 • 7.3K Ratings

🗓️ 30 October 2023

⏱️ 106 minutes

🔗️ Recording | iTunes | RSS

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Summary

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Kari Nadeau is a physician scientist with expertise in treating food allergies. In this episode, Kari first explains the fascinating workings of the immune system, exploring how it adeptly defends against bacteria and viruses but how the same system can lead to food allergies. She proceeds to explore the complexities of food allergies, detailing their typical developmental patterns, underscoring the significance of preventative approaches like early exposure, and highlighting the potentially life-threatening nature of severe food allergies. Kari illuminates the latest advancements in immunotherapies that not only mitigate allergy severity but also hold the potential to completely cure the patient. Additionally, Kari shares her concerns about the increasing levels of air pollution, elucidating its adverse effects on health while providing valuable suggestions for reducing exposure.

We discuss:

Kari’s motivation to study food allergies [4:00];
Overview of the immune system and the family of immunoglobulins [9:00];
How our immune system fights viruses, bacteria, or fungi, and some exceptions to the rule [13:00];
Why our immune system is generally better at fighting viruses than bacterial infections [18:45];
Differentiating a food sensitivity from a food allergy, and a discussion about celiac disease [25:30];
How food allergies develop, why they can be lethal, and factors contributing to the uptrend in food allergies [35:45];
The role of environmental factors in the onset of food allergies and strategies for prevention [50:15];
How immunotherapy helps to overcome, and even cure, food allergies [1:04:15];
Can immunotherapy work for environmental allergens like pollen? [1:24:00];
Air pollution: impact on health and tips for reducing your risk [1:25:30];
Resources for those wanting to learn more or find clinical trials related to food allergies [1:40:45]; and
More.

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Transcript

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0:00.0	Hey everyone, welcome to the Drive Podcast. I'm your host Peter Atilla. This podcast,
0:16.6	my website, and my weekly newsletter all focus on the goal of translating the science
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1:04.6	My guess this week is Dr. Carrie Nadoo. Carrie is the chair of the Department of Environmental
1:10.3	Health at Harvard's School of Public Health, a professor of climate and population studies
1:14.3	and the interim director of the Center for Climate Health and the Global Environment.
1:18.6	Carrie's research focuses on the study of immunologic mechanisms involved in the causes,
1:24.6	diagnoses, and therapy for allergies and asthma. Carrie earned her MD and PhD from Harvard
1:30.2	Medical School in 1995, completing her doctoral work in biochemistry and immunology. She's a member
1:35.1	of the National Academy of Medicine and has co-authored the book The End of Food Allergy, the first
1:40.8	program to prevent and reverse a 21st century epidemic. In this episode, we talk about how the
1:48.2	immune system works when it comes to fighting bacteria and viruses. Now, you might think,
1:52.8	well, what does this have to do with food allergies? Well, of course, it's because the same immune system
1:57.6	that correctly helps us fight off bacteria and viruses incorrectly gets wound up when it comes
	...

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