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High Intensity Health with Mike Mutzel, MS

25 vs 100 Grams of Protein Post-Workout for Muscle Gains: New Study Breakdown

High Intensity Health with Mike Mutzel, MS

Mike Mutzel

Fasting, Nutrition, Autophagy, Ketogenic, Keto, Health & Fitness, Ketodiet, Medicine

4.8 • 1.2K Ratings

🗓️ 6 January 2024

⏱️ 24 minutes

🧾️ Download transcript

Summary

A new study challenges the assumption that you can only absorb and utilize 25 grams of protein in one meal.

Anything more than this won’t increase muscle protein synthesis or anabolic signaling—those excess amino acids will be oxidized (broken down), the thinking went.

Scientists in the Netherlands challenged this old paradigm…

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Link to Research and Video: https://bit.ly/3NO3Afd

Episode Time Stamps:

0:00 Higher protein after exercise increases muscle protein synthesis.

0:45 Essential amino acids do not become oxidized even after 100 grams of protein.

2:00 You do not have to spread out your protein consumption.

3:45 Anabolic resistance is a phenomenon of aging, requiring more protein.

6:00 The more protein you have, the more anabolism you have.

8:00 Exercise and protein both build muscle.

9:10 Animals consume large amounts of protein infrequently.

12:18 There is no scientific proof that excess amino acids are being oxidized.

13:30 There are progressively increased levels of amino acids if you have sufficient protein, over the course of 12 hours.

17:00 There was a transient rise in insulin in the 100-gram group.

18:25 More protein translates into increased muscle protein synthesis at the level of the muscle tissue.

20:56 Amino acids are not preferentially oxidized as fuel or converted into glucose.

Transcript

Click on a timestamp to play from that location

0:00.0

A recently published study found that higher protein

0:02.4

after exercise translates into increased muscle protein synthesis.

0:06.8

In today's show we're going to dive into these details from a fascinating new study

0:10.6

titled The Anabolic Response to protein ingestion during recovery

0:13.8

from exercise has no upper limit in magnitude and duration in vivo in humans.

0:18.4

This was published recently in the journal Cell Reports Medicine.

0:22.3

Here is the graphical abstract abstract it's a really interesting

0:25.2

article because hitherto the old paradigm was that if you have more protein say more than

0:31.2

40 grams of protein it's really futile it doesn't really matter because

0:35.4

those amino acids from the protein sources will become oxidized meaning they

0:39.6

will not contribute to increased muscle protein synthesis in the post exercise window but this new study

0:45.0

finds that the essential amino acids like phenylalanine, methionine, lusine, isolucine, and valine

0:51.5

do not become oxidized even after having 100 grams of protein.

0:57.0

So what was unique about this study is they had young subjects undergo a resistance training session

1:01.8

and they randomize them to three different groups, either

1:04.0

having no protein in the post exercise window or 25 grams of protein in an exercise window or 100 grams

1:10.4

of protein.

1:11.4

And so what was unique about this study is they not only did

1:13.6

muscle biopsies in the post exercise window, but they drew blood in the 12 hour

1:17.6

window after exercise and found that the amino acids, even in the group that had

1:22.0

100 grams of protein in the post exercise

1:24.2

window those amino acids did not become oxidized and so again that is the old

...

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